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Prostate Cancer: Science and Clinical Practice

Population Screening for Prostate Cancer and Early Detection in High-risk African American Men

Publication ,  Chapter
Moul, JW
January 1, 2003

This chapter explores the changes in the prostate specific antigen (PSA) screening test and the prospects for targeted screening of certain groups of individuals who may be at particular risk of developing prostate cancer. Prostate cancer is the most common malignancy in American men, accounting for more than 29% of all diagnosed cancers and approximately 13% of all cancer deaths. To be of value, screening must lead to treatment that has a favorable impact on prognosis. Opponents of screening point to the potential for side effects from treatment, the possibility that some men will be treated unnecessarily, the economic burden on the health care system, and the lack of definitive scientific evidence that the screening will reduce overall disease-specific mortality. Although randomized clinical trials have yet to definitively prove or disprove the efficacy of prostate cancer population-based screening, emerging data in the PSA era arguably support PSA testing in the early diagnosis of prostate cancer. Specifically, with public awareness of the disease and widespread PSA testing, smaller cancers are being detected in younger men and survival rates are on the rise. Use of age- and race-specific reference ranges for PSA based on sensitivity, or maximal cancer detection, is a favorable approach in this high-risk group.

Duke Scholars

DOI

ISBN

9780122869815

Publication Date

January 1, 2003

Start / End Page

3 / 10
 

Citation

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Moul, J. W. (2003). Population Screening for Prostate Cancer and Early Detection in High-risk African American Men. In Prostate Cancer: Science and Clinical Practice (pp. 3–10). https://doi.org/10.1016/B978-012286981-5/50003-3
Moul, J. W. “Population Screening for Prostate Cancer and Early Detection in High-risk African American Men.” In Prostate Cancer: Science and Clinical Practice, 3–10, 2003. https://doi.org/10.1016/B978-012286981-5/50003-3.
Moul JW. Population Screening for Prostate Cancer and Early Detection in High-risk African American Men. In: Prostate Cancer: Science and Clinical Practice. 2003. p. 3–10.
Moul, J. W. “Population Screening for Prostate Cancer and Early Detection in High-risk African American Men.” Prostate Cancer: Science and Clinical Practice, 2003, pp. 3–10. Scopus, doi:10.1016/B978-012286981-5/50003-3.
Moul JW. Population Screening for Prostate Cancer and Early Detection in High-risk African American Men. Prostate Cancer: Science and Clinical Practice. 2003. p. 3–10.
Journal cover image

DOI

ISBN

9780122869815

Publication Date

January 1, 2003

Start / End Page

3 / 10