Non-Hodgkin's lymphomas, version 2.2014.
Non-Hodgkin's lymphomas (NHLs) are a heterogeneous group of lymphoproliferative disorders originating in B lymphocytes, T lymphocytes, or natural killer cells. Follicular lymphoma (FL) is the most common subtype of indolent NHL, accounting for approximately 22% of all newly diagnosed cases of NHL. The incorporation of rituximab to chemotherapy regimens has become a widely accepted standard of care for first-line therapy for patients with FL. Maintenance and consolidation therapy with rituximab and radioimmunotherapy have also been associated with improved progression-free survival in patients experiencing response to first-line therapy. Despite therapeutic advances that have improved outcomes, FL is generally considered a chronic disease characterized by multiple recurrences with current therapies. This manuscript discusses the recommendations outlined in the NCCN Guidelines for the diagnosis and management of patients with FL.
Duke Scholars
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Related Subject Headings
- Rituximab
- Radioimmunotherapy
- Oncology & Carcinogenesis
- Neoplasm Recurrence, Local
- Lymphoma, Non-Hodgkin
- Lymphoma, Follicular
- Humans
- Disease-Free Survival
- Antineoplastic Combined Chemotherapy Protocols
- Antibodies, Monoclonal, Murine-Derived
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Rituximab
- Radioimmunotherapy
- Oncology & Carcinogenesis
- Neoplasm Recurrence, Local
- Lymphoma, Non-Hodgkin
- Lymphoma, Follicular
- Humans
- Disease-Free Survival
- Antineoplastic Combined Chemotherapy Protocols
- Antibodies, Monoclonal, Murine-Derived