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Breast cancer and aging: results of the U13 conference breast cancer panel.

Publication ,  Journal Article
Barginear, MF; Muss, H; Kimmick, G; Owusu, C; Mrozek, E; Shahrokni, A; Ballman, K; Hurria, A
Published in: Breast Cancer Res Treat
July 2014

Breast cancer is predominantly a disease of older women, yet there is a knowledge gap due to the persisting misalignment between the age distribution of women with breast cancer and the age distribution of participants in clinical trials. The purpose of this report is to state the U13 conference breast cancer panel's recommendations regarding therapeutic clinical trials that will fill gaps in knowledge regarding the care of older patients with breast cancer. The U13 conference was a collaboration between the Cancer and Aging Research Group and the National Institute on Aging and the National Cancer Institute (NCI). Clinical trials should be developed for frail and vulnerable patients who would not enroll on the standard phase III trials, as well as efforts need to be made to increase enrollment of fit older patients on standard phase III trials. As a result of this conference, panel members are working with the NCI and cooperative groups to address these knowledge gaps. With the aging population and increasing incidence of breast cancer with age, it is essential to study the feasibility, toxicity, and efficacy of cancer therapy in this at-risk population.

Duke Scholars

Published In

Breast Cancer Res Treat

DOI

EISSN

1573-7217

Publication Date

July 2014

Volume

146

Issue

1

Start / End Page

1 / 6

Location

Netherlands

Related Subject Headings

  • Oncology & Carcinogenesis
  • Neoplasm Metastasis
  • Middle Aged
  • Humans
  • Female
  • Breast Neoplasms
  • Aging
  • Aged, 80 and over
  • Aged
  • Age Factors
 

Citation

APA
Chicago
ICMJE
MLA
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Barginear, M. F., Muss, H., Kimmick, G., Owusu, C., Mrozek, E., Shahrokni, A., … Hurria, A. (2014). Breast cancer and aging: results of the U13 conference breast cancer panel. Breast Cancer Res Treat, 146(1), 1–6. https://doi.org/10.1007/s10549-014-2994-7
Barginear, M. F., H. Muss, G. Kimmick, C. Owusu, E. Mrozek, A. Shahrokni, K. Ballman, and A. Hurria. “Breast cancer and aging: results of the U13 conference breast cancer panel.Breast Cancer Res Treat 146, no. 1 (July 2014): 1–6. https://doi.org/10.1007/s10549-014-2994-7.
Barginear MF, Muss H, Kimmick G, Owusu C, Mrozek E, Shahrokni A, et al. Breast cancer and aging: results of the U13 conference breast cancer panel. Breast Cancer Res Treat. 2014 Jul;146(1):1–6.
Barginear, M. F., et al. “Breast cancer and aging: results of the U13 conference breast cancer panel.Breast Cancer Res Treat, vol. 146, no. 1, July 2014, pp. 1–6. Pubmed, doi:10.1007/s10549-014-2994-7.
Barginear MF, Muss H, Kimmick G, Owusu C, Mrozek E, Shahrokni A, Ballman K, Hurria A. Breast cancer and aging: results of the U13 conference breast cancer panel. Breast Cancer Res Treat. 2014 Jul;146(1):1–6.
Journal cover image

Published In

Breast Cancer Res Treat

DOI

EISSN

1573-7217

Publication Date

July 2014

Volume

146

Issue

1

Start / End Page

1 / 6

Location

Netherlands

Related Subject Headings

  • Oncology & Carcinogenesis
  • Neoplasm Metastasis
  • Middle Aged
  • Humans
  • Female
  • Breast Neoplasms
  • Aging
  • Aged, 80 and over
  • Aged
  • Age Factors