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Management of anticoagulation agents in trauma patients.

Publication ,  Journal Article
McCoy, CC; Lawson, JH; Shapiro, ML
Published in: Clin Lab Med
September 2014

A lack of consensus on anticoagulant reversal during acute trauma is compounded by an aging population and the expanding spectrum of new anticoagulation agents. Developments in laboratory assays and transfusion medicine, including thromboelastography, recombinant factors, and factor concentrates, have revolutionized care for anticoagulated trauma patients. Accordingly, clinicians must be fully aware of drug mechanisms, assays to determine drug activity, and appropriate reversal strategies for patients on anticoagulants. Drugs include vitamin K antagonists, direct thrombin inhibitors, direct factor Xa inhibitors, low molecular weight heparin, and antiplatelet agents. This article discusses the appropriate assessment and management of trauma patients receiving these agents.

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Published In

Clin Lab Med

DOI

EISSN

1557-9832

Publication Date

September 2014

Volume

34

Issue

3

Start / End Page

563 / 574

Location

United States

Related Subject Headings

  • Wounds and Injuries
  • Pathology
  • Humans
  • Hemorrhage
  • Emergency Treatment
  • Drug Monitoring
  • Anticoagulants
  • Animals
  • Administration, Oral
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
McCoy, C. C., Lawson, J. H., & Shapiro, M. L. (2014). Management of anticoagulation agents in trauma patients. Clin Lab Med, 34(3), 563–574. https://doi.org/10.1016/j.cll.2014.06.013
McCoy, C Cameron, Jeffrey H. Lawson, and Mark L. Shapiro. “Management of anticoagulation agents in trauma patients.Clin Lab Med 34, no. 3 (September 2014): 563–74. https://doi.org/10.1016/j.cll.2014.06.013.
McCoy CC, Lawson JH, Shapiro ML. Management of anticoagulation agents in trauma patients. Clin Lab Med. 2014 Sep;34(3):563–74.
McCoy, C. Cameron, et al. “Management of anticoagulation agents in trauma patients.Clin Lab Med, vol. 34, no. 3, Sept. 2014, pp. 563–74. Pubmed, doi:10.1016/j.cll.2014.06.013.
McCoy CC, Lawson JH, Shapiro ML. Management of anticoagulation agents in trauma patients. Clin Lab Med. 2014 Sep;34(3):563–574.
Journal cover image

Published In

Clin Lab Med

DOI

EISSN

1557-9832

Publication Date

September 2014

Volume

34

Issue

3

Start / End Page

563 / 574

Location

United States

Related Subject Headings

  • Wounds and Injuries
  • Pathology
  • Humans
  • Hemorrhage
  • Emergency Treatment
  • Drug Monitoring
  • Anticoagulants
  • Animals
  • Administration, Oral
  • 3202 Clinical sciences