Potential applications of pharmacogenomics to heart failure therapies.
Publication
, Journal Article
Parikh, KS; Ahmad, T; Fiuzat, M
Published in: Heart Fail Clin
October 2014
Pharmacogenomics explores one drug's varying effects on different patient genotypes. A better understanding of genomic variation's contribution to drug response can impact 4 arenas in heart failure (HF): (1) identification of patients most likely to receive benefit from therapy, (2) risk stratify patients for risk of adverse events, (3) optimize dosing of drugs, and (4) steer future clinical trial design and drug development. In this review, the authors explore the potential applications of pharmacogenomics in patients with HF in the context of these categories.
Duke Scholars
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Published In
Heart Fail Clin
DOI
ISSN
1551-7136
Publication Date
October 2014
Volume
10
Issue
4
Start / End Page
599 / 606
Location
United States
Related Subject Headings
- Pharmacogenetics
- Humans
- Heart Failure
- Death, Sudden, Cardiac
- Cardiovascular System & Hematology
- 3201 Cardiovascular medicine and haematology
Citation
APA
Chicago
ICMJE
MLA
NLM
Parikh, K. S., Ahmad, T., & Fiuzat, M. (2014). Potential applications of pharmacogenomics to heart failure therapies. Heart Fail Clin, 10(4), 599–606. https://doi.org/10.1016/j.hfc.2014.07.007
Parikh, Kishan S., Tariq Ahmad, and Mona Fiuzat. “Potential applications of pharmacogenomics to heart failure therapies.” Heart Fail Clin 10, no. 4 (October 2014): 599–606. https://doi.org/10.1016/j.hfc.2014.07.007.
Parikh KS, Ahmad T, Fiuzat M. Potential applications of pharmacogenomics to heart failure therapies. Heart Fail Clin. 2014 Oct;10(4):599–606.
Parikh, Kishan S., et al. “Potential applications of pharmacogenomics to heart failure therapies.” Heart Fail Clin, vol. 10, no. 4, Oct. 2014, pp. 599–606. Pubmed, doi:10.1016/j.hfc.2014.07.007.
Parikh KS, Ahmad T, Fiuzat M. Potential applications of pharmacogenomics to heart failure therapies. Heart Fail Clin. 2014 Oct;10(4):599–606.
Published In
Heart Fail Clin
DOI
ISSN
1551-7136
Publication Date
October 2014
Volume
10
Issue
4
Start / End Page
599 / 606
Location
United States
Related Subject Headings
- Pharmacogenetics
- Humans
- Heart Failure
- Death, Sudden, Cardiac
- Cardiovascular System & Hematology
- 3201 Cardiovascular medicine and haematology