Skip to main content

Magnetographic array for the capture and enumeration of single cells and cell pairs.

Publication ,  Journal Article
Shields, CW; Livingston, CE; Yellen, BB; López, GP; Murdoch, DM
Published in: Biomicrofluidics
July 2014

We present a simple microchip device consisting of an overlaid pattern of micromagnets and microwells capable of capturing magnetically labeled cells into well-defined compartments (with accuracies >95%). Its flexible design permits the programmable deposition of single cells for their direct enumeration and pairs of cells for the detailed analysis of cell-cell interactions. This cell arraying device requires no external power and can be operated solely with permanent magnets. Large scale image analysis of cells captured in this array can yield valuable information (e.g., regarding various immune parameters such as the CD4:CD8 ratio) in a miniaturized and portable platform.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Biomicrofluidics

DOI

ISSN

1932-1058

Publication Date

July 2014

Volume

8

Issue

4

Start / End Page

041101

Location

United States

Related Subject Headings

  • Nanoscience & Nanotechnology
  • 4012 Fluid mechanics and thermal engineering
  • 1007 Nanotechnology
  • 0915 Interdisciplinary Engineering
  • 0203 Classical Physics
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Shields, C. W., Livingston, C. E., Yellen, B. B., López, G. P., & Murdoch, D. M. (2014). Magnetographic array for the capture and enumeration of single cells and cell pairs. Biomicrofluidics, 8(4), 041101. https://doi.org/10.1063/1.4885840
Shields, C Wyatt, Carissa E. Livingston, Benjamin B. Yellen, Gabriel P. López, and David M. Murdoch. “Magnetographic array for the capture and enumeration of single cells and cell pairs.Biomicrofluidics 8, no. 4 (July 2014): 041101. https://doi.org/10.1063/1.4885840.
Shields CW, Livingston CE, Yellen BB, López GP, Murdoch DM. Magnetographic array for the capture and enumeration of single cells and cell pairs. Biomicrofluidics. 2014 Jul;8(4):041101.
Shields, C. Wyatt, et al. “Magnetographic array for the capture and enumeration of single cells and cell pairs.Biomicrofluidics, vol. 8, no. 4, July 2014, p. 041101. Pubmed, doi:10.1063/1.4885840.
Shields CW, Livingston CE, Yellen BB, López GP, Murdoch DM. Magnetographic array for the capture and enumeration of single cells and cell pairs. Biomicrofluidics. 2014 Jul;8(4):041101.

Published In

Biomicrofluidics

DOI

ISSN

1932-1058

Publication Date

July 2014

Volume

8

Issue

4

Start / End Page

041101

Location

United States

Related Subject Headings

  • Nanoscience & Nanotechnology
  • 4012 Fluid mechanics and thermal engineering
  • 1007 Nanotechnology
  • 0915 Interdisciplinary Engineering
  • 0203 Classical Physics