Regulation of appetite to treat obesity.
Publication
, Journal Article
Kim, GW; Lin, JE; Valentino, MA; Colon-Gonzalez, F; Waldman, SA
Published in: Expert Rev Clin Pharmacol
March 2011
Obesity has escalated into a pandemic over the past few decades. In turn, research efforts have sought to elucidate the molecular mechanisms underlying the regulation of energy balance. A host of endogenous mediators regulate appetite and metabolism, and thereby control both short- and long-term energy balance. These mediators, which include gut, pancreatic and adipose neuropeptides, have been targeted in the development of anti-obesity pharmacotherapy, with the goal of amplifying anorexigenic and lipolytic signaling or blocking orexigenic and lipogenic signaling. This article presents the efficacy and safety of these anti-obesity drugs.
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Published In
Expert Rev Clin Pharmacol
DOI
EISSN
1751-2441
Publication Date
March 2011
Volume
4
Issue
2
Start / End Page
243 / 259
Location
England
Related Subject Headings
- Treatment Outcome
- Pharmacology & Pharmacy
- Obesity
- Humans
- Eating
- Appetite Regulation
- Appetite
- Anti-Obesity Agents
- Animals
- 3214 Pharmacology and pharmaceutical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Kim, G. W., Lin, J. E., Valentino, M. A., Colon-Gonzalez, F., & Waldman, S. A. (2011). Regulation of appetite to treat obesity. Expert Rev Clin Pharmacol, 4(2), 243–259. https://doi.org/10.1586/ecp.11.3
Kim, Gilbert W., Jieru E. Lin, Michael A. Valentino, Francheska Colon-Gonzalez, and Scott A. Waldman. “Regulation of appetite to treat obesity.” Expert Rev Clin Pharmacol 4, no. 2 (March 2011): 243–59. https://doi.org/10.1586/ecp.11.3.
Kim GW, Lin JE, Valentino MA, Colon-Gonzalez F, Waldman SA. Regulation of appetite to treat obesity. Expert Rev Clin Pharmacol. 2011 Mar;4(2):243–59.
Kim, Gilbert W., et al. “Regulation of appetite to treat obesity.” Expert Rev Clin Pharmacol, vol. 4, no. 2, Mar. 2011, pp. 243–59. Pubmed, doi:10.1586/ecp.11.3.
Kim GW, Lin JE, Valentino MA, Colon-Gonzalez F, Waldman SA. Regulation of appetite to treat obesity. Expert Rev Clin Pharmacol. 2011 Mar;4(2):243–259.
Published In
Expert Rev Clin Pharmacol
DOI
EISSN
1751-2441
Publication Date
March 2011
Volume
4
Issue
2
Start / End Page
243 / 259
Location
England
Related Subject Headings
- Treatment Outcome
- Pharmacology & Pharmacy
- Obesity
- Humans
- Eating
- Appetite Regulation
- Appetite
- Anti-Obesity Agents
- Animals
- 3214 Pharmacology and pharmaceutical sciences