Induction immunosuppression in liver transplantation: a review.
Publication
, Journal Article
Turner, AP; Knechtle, SJ
Published in: Transpl Int
July 2013
Antibody therapy for induction is seldom used in liver transplantation in the United States, but continues to be used in approximately 10% of patients. The most commonly used antibody at the current time is basiliximab (Simulect, Novartis) and is used in adults with renal dysfunction at the time of liver transplantation with the intention of delaying introduction of calcineurin-inhibitors. In children, the same antibody is commonly used in order to reduce rates of acute rejection. Most patients, adult and pediatric, are treated with initially higher levels of tacrolimus rather than antibody induction.
Duke Scholars
Published In
Transpl Int
DOI
EISSN
1432-2277
Publication Date
July 2013
Volume
26
Issue
7
Start / End Page
673 / 683
Location
Switzerland
Related Subject Headings
- Surgery
- Recurrence
- Recombinant Fusion Proteins
- Receptors, Interleukin-2
- Liver Transplantation
- Immunosuppressive Agents
- Humans
- Hepatitis C
- Graft Rejection
- Calcineurin Inhibitors
Citation
APA
Chicago
ICMJE
MLA
NLM
Turner, A. P., & Knechtle, S. J. (2013). Induction immunosuppression in liver transplantation: a review. Transpl Int, 26(7), 673–683. https://doi.org/10.1111/tri.12100
Turner, Alexandra P., and Stuart J. Knechtle. “Induction immunosuppression in liver transplantation: a review.” Transpl Int 26, no. 7 (July 2013): 673–83. https://doi.org/10.1111/tri.12100.
Turner AP, Knechtle SJ. Induction immunosuppression in liver transplantation: a review. Transpl Int. 2013 Jul;26(7):673–83.
Turner, Alexandra P., and Stuart J. Knechtle. “Induction immunosuppression in liver transplantation: a review.” Transpl Int, vol. 26, no. 7, July 2013, pp. 673–83. Pubmed, doi:10.1111/tri.12100.
Turner AP, Knechtle SJ. Induction immunosuppression in liver transplantation: a review. Transpl Int. 2013 Jul;26(7):673–683.
Published In
Transpl Int
DOI
EISSN
1432-2277
Publication Date
July 2013
Volume
26
Issue
7
Start / End Page
673 / 683
Location
Switzerland
Related Subject Headings
- Surgery
- Recurrence
- Recombinant Fusion Proteins
- Receptors, Interleukin-2
- Liver Transplantation
- Immunosuppressive Agents
- Humans
- Hepatitis C
- Graft Rejection
- Calcineurin Inhibitors