Skip to main content

Effect of diabetes mellitus on giant cell arteritis.

Publication ,  Journal Article
Abel, AS; Yashkin, AP; Sloan, FA; Lee, MS
Published in: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
June 2015

To determine if Type 2 diabetes mellitus (DM) is protective against giant cell arteritis (GCA) and to estimate the incidence of GCA diagnosis from Medicare claims.Medicare 5% claims files from 1991 to 2011 were used to identify beneficiaries diagnosed with DM, but not GCA, within a 3-year ascertainment period. Propensity score matching was used to define a control group of nondiabetics with comparable demographic covariates. Competing risk regression was then used to assess the impact of DM diagnosis on GCA diagnosis. To allow for a 3-year ascertainment period, the analysis sample was limited to beneficiaries older than 68 years at baseline.A total of 151,041 beneficiaries diagnosed with DM were matched to an equal number of controls. Mean study follow-up was 67.75 months. GCA was diagnosed among 1116 beneficiaries with DM (0.73%) vs 465 (0.30%) controls. The risk of receiving a GCA diagnosis among patients with DM was increased by 100% (subhazard ratio, 2.00; 95% confidence interval, 1.78-2.25). The annual incidence of GCA diagnosis among claims for US Medicare beneficiaries older than 68 years old was 93 in 100,000.A DM diagnosis is not protective against a GCA diagnosis in the Medicare population. Our data suggest that a DM diagnosis increases the risk of GCA diagnosis within 5.7 years for Medicare beneficiaries older than 68 years.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

DOI

EISSN

1536-5166

ISSN

1070-8022

Publication Date

June 2015

Volume

35

Issue

2

Start / End Page

134 / 138

Related Subject Headings

  • United States
  • Retrospective Studies
  • Ophthalmology & Optometry
  • Medicare
  • Male
  • Humans
  • Giant Cell Arteritis
  • Female
  • Diabetes Mellitus
  • 3212 Ophthalmology and optometry
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Abel, A. S., Yashkin, A. P., Sloan, F. A., & Lee, M. S. (2015). Effect of diabetes mellitus on giant cell arteritis. Journal of Neuro-Ophthalmology : The Official Journal of the North American Neuro-Ophthalmology Society, 35(2), 134–138. https://doi.org/10.1097/wno.0000000000000218
Abel, Anne S., Arseniy P. Yashkin, Frank A. Sloan, and Michael S. Lee. “Effect of diabetes mellitus on giant cell arteritis.Journal of Neuro-Ophthalmology : The Official Journal of the North American Neuro-Ophthalmology Society 35, no. 2 (June 2015): 134–38. https://doi.org/10.1097/wno.0000000000000218.
Abel AS, Yashkin AP, Sloan FA, Lee MS. Effect of diabetes mellitus on giant cell arteritis. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 2015 Jun;35(2):134–8.
Abel, Anne S., et al. “Effect of diabetes mellitus on giant cell arteritis.Journal of Neuro-Ophthalmology : The Official Journal of the North American Neuro-Ophthalmology Society, vol. 35, no. 2, June 2015, pp. 134–38. Epmc, doi:10.1097/wno.0000000000000218.
Abel AS, Yashkin AP, Sloan FA, Lee MS. Effect of diabetes mellitus on giant cell arteritis. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 2015 Jun;35(2):134–138.

Published In

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

DOI

EISSN

1536-5166

ISSN

1070-8022

Publication Date

June 2015

Volume

35

Issue

2

Start / End Page

134 / 138

Related Subject Headings

  • United States
  • Retrospective Studies
  • Ophthalmology & Optometry
  • Medicare
  • Male
  • Humans
  • Giant Cell Arteritis
  • Female
  • Diabetes Mellitus
  • 3212 Ophthalmology and optometry