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The future of cardiovascular clinical research in North America and beyond-addressing challenges and leveraging opportunities through unique academic and grassroots collaborations.

Publication ,  Journal Article
Roe, MT; Mahaffey, KW; Ezekowitz, JA; Alexander, JH; Goodman, SG; Hernandez, A; Temple, T; Berdan, L; Califf, RM; Harrington, RA; Peterson, ED ...
Published in: Am Heart J
June 2015

Recent developments have highlighted the challenges facing cardiovascular clinical research in global contemporary practice, particularly in North America, including shifting priorities for drug development targets, increasing regulatory requirements, and expensive operational approaches for conducting randomized clinical trials. Nonetheless, emerging trends such as the consolidation of practices and hospitals into integrated health systems, the integration of electronic health records from thousands of practices into large data repositories to support prospective research studies, and streamlined operational approaches such as registry-based trials and risk-based monitoring have created numerous opportunities to disrupt the clinical research paradigm. Within this context, academic research organizations around the globe, particularly a strengthened collaboration of 3 established academic research organizations in North America, are uniquely positioned to promote and develop grassroots collaborations across all types of clinical practices, to delineate successful solutions to obstacles that limit clinical research initiatives, and to guide the future of cardiovascular research in the global research environment.

Duke Scholars

Published In

Am Heart J

DOI

EISSN

1097-6744

Publication Date

June 2015

Volume

169

Issue

6

Start / End Page

743 / 750

Location

United States

Related Subject Headings

  • Research Support as Topic
  • North America
  • Interprofessional Relations
  • Humans
  • Forecasting
  • Cooperative Behavior
  • Clinical Trials as Topic
  • Cardiovascular System & Hematology
  • Cardiology
  • Biomedical Research
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Roe, M. T., Mahaffey, K. W., Ezekowitz, J. A., Alexander, J. H., Goodman, S. G., Hernandez, A., … Armstrong, P. W. (2015). The future of cardiovascular clinical research in North America and beyond-addressing challenges and leveraging opportunities through unique academic and grassroots collaborations. Am Heart J, 169(6), 743–750. https://doi.org/10.1016/j.ahj.2015.03.002
Roe, Matthew T., Kenneth W. Mahaffey, Justin A. Ezekowitz, John H. Alexander, Shaun G. Goodman, Adrian Hernandez, Tracy Temple, et al. “The future of cardiovascular clinical research in North America and beyond-addressing challenges and leveraging opportunities through unique academic and grassroots collaborations.Am Heart J 169, no. 6 (June 2015): 743–50. https://doi.org/10.1016/j.ahj.2015.03.002.
Roe, Matthew T., et al. “The future of cardiovascular clinical research in North America and beyond-addressing challenges and leveraging opportunities through unique academic and grassroots collaborations.Am Heart J, vol. 169, no. 6, June 2015, pp. 743–50. Pubmed, doi:10.1016/j.ahj.2015.03.002.
Roe MT, Mahaffey KW, Ezekowitz JA, Alexander JH, Goodman SG, Hernandez A, Temple T, Berdan L, Califf RM, Harrington RA, Peterson ED, Armstrong PW. The future of cardiovascular clinical research in North America and beyond-addressing challenges and leveraging opportunities through unique academic and grassroots collaborations. Am Heart J. 2015 Jun;169(6):743–750.
Journal cover image

Published In

Am Heart J

DOI

EISSN

1097-6744

Publication Date

June 2015

Volume

169

Issue

6

Start / End Page

743 / 750

Location

United States

Related Subject Headings

  • Research Support as Topic
  • North America
  • Interprofessional Relations
  • Humans
  • Forecasting
  • Cooperative Behavior
  • Clinical Trials as Topic
  • Cardiovascular System & Hematology
  • Cardiology
  • Biomedical Research