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Chronic lymphocytic leukemia/small lymphocytic lymphoma, version 1.2015.

Publication ,  Journal Article
Zelenetz, AD; Gordon, LI; Wierda, WG; Abramson, JS; Advani, RH; Andreadis, CB; Bartlett, N; Byrd, JC; Czuczman, MS; Fayad, LE; Fisher, RI ...
Published in: J Natl Compr Canc Netw
March 2015
Published version (DOI) Link to item

Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are different manifestations of the same disease, which are managed in the same way. The advent of novel monoclonal antibodies (ofatumumab and obinutuzumab) led to the development of effective chemoimmunotherapy regimens. The recently approved small molecule kinase inhibitors (ibrutinib and idelalisib) are effective treatment options for CLL in elderly patients with decreased tolerance for aggressive regimens and in patients with poor prognostic features who do not benefit from conventional chemoimmunotherapy regimens. This portion of the NCCN Guidelines for Non-Hodgkin's Lymphomas describes the recent specific to the incorporation of recently approved targeted therapies for the management of patients with newly diagnosed and relapsed or refractory CLL/SLL.

Duke Scholars

Christopher Ryan Kelsey
Author Christopher Ryan Kelsey Radiation Oncology
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Published In

J Natl Compr Canc Netw

DOI

10.6004/jnccn.2015.0045

EISSN

1540-1413

Publication Date

March 2015

Volume

13

Issue

3

Start / End Page

326 / 362

Location

United States

Related Subject Headings

  • Prognosis
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Leukemia, Lymphocytic, Chronic, B-Cell
  • Humans
  • Disease Management
  • Comorbidity
  • Algorithms
  • 4203 Health services and systems
  • 3211 Oncology and carcinogenesis
 

Citation

APA
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ICMJE
MLA
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Zelenetz, A. D., Gordon, L. I., Wierda, W. G., Abramson, J. S., Advani, R. H., Andreadis, C. B., … National comprehension cancer network, . (2015). Chronic lymphocytic leukemia/small lymphocytic lymphoma, version 1.2015. J Natl Compr Canc Netw, 13(3), 326–362. https://doi.org/10.6004/jnccn.2015.0045
Zelenetz, Andrew D., Leo I. Gordon, William G. Wierda, Jeremy S. Abramson, Ranjana H. Advani, C Babis Andreadis, Nancy Bartlett, et al. “Chronic lymphocytic leukemia/small lymphocytic lymphoma, version 1.2015.” J Natl Compr Canc Netw 13, no. 3 (March 2015): 326–62. https://doi.org/10.6004/jnccn.2015.0045.
Zelenetz AD, Gordon LI, Wierda WG, Abramson JS, Advani RH, Andreadis CB, et al. Chronic lymphocytic leukemia/small lymphocytic lymphoma, version 1.2015. J Natl Compr Canc Netw. 2015 Mar;13(3):326–62.
Zelenetz, Andrew D., et al. “Chronic lymphocytic leukemia/small lymphocytic lymphoma, version 1.2015.” J Natl Compr Canc Netw, vol. 13, no. 3, Mar. 2015, pp. 326–62. Pubmed, doi:10.6004/jnccn.2015.0045.
Zelenetz AD, Gordon LI, Wierda WG, Abramson JS, Advani RH, Andreadis CB, Bartlett N, Byrd JC, Czuczman MS, Fayad LE, Fisher RI, Glenn MJ, Habermann TM, Harris NL, Hoppe RT, Horwitz SM, Kelsey CR, Kim YH, Krivacic S, LaCasce AS, Nademanee A, Porcu P, Press O, Rabinovitch R, Reddy N, Reid E, Saad AA, Sokol L, Swinnen LJ, Tsien C, Vose JM, Wilson L, Yahalom J, Zafar N, Dwyer M, Sundar H, National comprehension cancer network. Chronic lymphocytic leukemia/small lymphocytic lymphoma, version 1.2015. J Natl Compr Canc Netw. 2015 Mar;13(3):326–362.

Published In

J Natl Compr Canc Netw

DOI

10.6004/jnccn.2015.0045

EISSN

1540-1413

Publication Date

March 2015

Volume

13

Issue

3

Start / End Page

326 / 362

Location

United States

Related Subject Headings

  • Prognosis
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Leukemia, Lymphocytic, Chronic, B-Cell
  • Humans
  • Disease Management
  • Comorbidity
  • Algorithms
  • 4203 Health services and systems
  • 3211 Oncology and carcinogenesis