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Infertility and Assisted Reproduction

Ectopic and heterotopic pregnancies following in vitro fertilization

Publication ,  Chapter
Hubayter, ZR; Muasher, SJ
January 1, 2008

Introduction, Ectopic pregnancy is defined as an abnormal implantation of the conceptus in a location outside the uterine cavity. Heterotopic pregnancy is when there are concomitant intrauterine and extrauterine pregnancies (1). Ectopic pregnancy is a life-threatening condition and is one of the leading causes of maternal mortality. It accounts for 9 percent of all pregnancy-related deaths and is the most common etiology of maternal deaths in the first trimester (2). Assisted reproductive technologies (ART) are associated with several medical complications. These include ovarian hyperstimulation syndrome, bleeding, infections (ovarian abcess and endometritis), and a higher incidence of ectopic pregnancies. The incidence of ectopic pregnancies is increased in ART due to a higher number of embryos transferred and a higher prevalence of tubal disease in patients undergoing in vitro fertilization (IVF) (3). Abulcasis was the first to describe an ectopic pregnancy in the tenth century AD. He was an Arabic writer and one of the first to perform and discuss different types of surgical procedures. He discussed a case where he was able to retrieve fetal parts from a draining abdominal wound (4). Riolan, in the early seventeenth century, described a woman who died at four months of gestation. She presented with acute abdominal pain and syncope. Later, a fetus was identified in one of her fallopian tubes (5). In 1708, Duverney described a heterotopic pregnancy on autopsy (4).

Duke Scholars

DOI

ISBN

9780521873796

Publication Date

January 1, 2008

Start / End Page

619 / 628
 

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Hubayter, Z. R., & Muasher, S. J. (2008). Ectopic and heterotopic pregnancies following in vitro fertilization. In Infertility and Assisted Reproduction (pp. 619–628). https://doi.org/10.1017/CBO9780511547287.066
Hubayter, Z. R., and S. J. Muasher. “Ectopic and heterotopic pregnancies following in vitro fertilization.” In Infertility and Assisted Reproduction, 619–28, 2008. https://doi.org/10.1017/CBO9780511547287.066.
Hubayter ZR, Muasher SJ. Ectopic and heterotopic pregnancies following in vitro fertilization. In: Infertility and Assisted Reproduction. 2008. p. 619–28.
Hubayter, Z. R., and S. J. Muasher. “Ectopic and heterotopic pregnancies following in vitro fertilization.” Infertility and Assisted Reproduction, 2008, pp. 619–28. Scopus, doi:10.1017/CBO9780511547287.066.
Hubayter ZR, Muasher SJ. Ectopic and heterotopic pregnancies following in vitro fertilization. Infertility and Assisted Reproduction. 2008. p. 619–628.
Journal cover image

DOI

ISBN

9780521873796

Publication Date

January 1, 2008

Start / End Page

619 / 628