Clinical application of whole-genome sequencing in patients with primary immunodeficiency.
Publication
, Journal Article
Mousallem, T; Urban, TJ; McSweeney, KM; Kleinstein, SE; Zhu, M; Adeli, M; Parrott, RE; Roberts, JL; Krueger, B; Buckley, RH; Goldstein, DB
Published in: J Allergy Clin Immunol
August 2015
This report illustrates the value of whole genome sequencing (WGS) in elucidating the genetic cause of disease in patients with primary immunodeficiency (PID). As sequencing costs decline, we predict that utilization of next generation sequencing (NGS) in the clinical setting will increase.
Duke Scholars
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Published In
J Allergy Clin Immunol
DOI
EISSN
1097-6825
Publication Date
August 2015
Volume
136
Issue
2
Start / End Page
476 / 9.e6
Location
United States
Related Subject Headings
- T-Lymphocytes
- Nuclear Proteins
- NADPH Oxidases
- Mutation
- Molecular Sequence Data
- Male
- Lymphocyte Count
- Killer Cells, Natural
- Immunologic Deficiency Syndromes
- Immunoglobulin G
Citation
APA
Chicago
ICMJE
MLA
NLM
Mousallem, T., Urban, T. J., McSweeney, K. M., Kleinstein, S. E., Zhu, M., Adeli, M., … Goldstein, D. B. (2015). Clinical application of whole-genome sequencing in patients with primary immunodeficiency. J Allergy Clin Immunol, 136(2), 476-9.e6. https://doi.org/10.1016/j.jaci.2015.02.040
Mousallem, Talal, Thomas J. Urban, K Melodi McSweeney, Sarah E. Kleinstein, Mingfu Zhu, Mehdi Adeli, Roberta E. Parrott, et al. “Clinical application of whole-genome sequencing in patients with primary immunodeficiency.” J Allergy Clin Immunol 136, no. 2 (August 2015): 476-9.e6. https://doi.org/10.1016/j.jaci.2015.02.040.
Mousallem T, Urban TJ, McSweeney KM, Kleinstein SE, Zhu M, Adeli M, et al. Clinical application of whole-genome sequencing in patients with primary immunodeficiency. J Allergy Clin Immunol. 2015 Aug;136(2):476-9.e6.
Mousallem, Talal, et al. “Clinical application of whole-genome sequencing in patients with primary immunodeficiency.” J Allergy Clin Immunol, vol. 136, no. 2, Aug. 2015, pp. 476-9.e6. Pubmed, doi:10.1016/j.jaci.2015.02.040.
Mousallem T, Urban TJ, McSweeney KM, Kleinstein SE, Zhu M, Adeli M, Parrott RE, Roberts JL, Krueger B, Buckley RH, Goldstein DB. Clinical application of whole-genome sequencing in patients with primary immunodeficiency. J Allergy Clin Immunol. 2015 Aug;136(2):476–9.e6.
Published In
J Allergy Clin Immunol
DOI
EISSN
1097-6825
Publication Date
August 2015
Volume
136
Issue
2
Start / End Page
476 / 9.e6
Location
United States
Related Subject Headings
- T-Lymphocytes
- Nuclear Proteins
- NADPH Oxidases
- Mutation
- Molecular Sequence Data
- Male
- Lymphocyte Count
- Killer Cells, Natural
- Immunologic Deficiency Syndromes
- Immunoglobulin G