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Interleukin-21: a multifunctional regulator of immunity to infections.

Publication ,  Journal Article
Yi, JS; Cox, MA; Zajac, AJ
Published in: Microbes Infect
December 2010

Interleukin-21 (IL-21) is a cytokine that has broad effects on both innate and adaptive immune responses. The roles of IL-21 in determining immunity to infections are currently being defined, and notably, it has been shown that IL-21 is most critical for sustaining T cell responses during chronic viral infections. This article discusses our current understanding of the immunobiology of IL-21, as well as its known and potential roles in influencing immunity to infections.

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Published In

Microbes Infect

DOI

EISSN

1769-714X

Publication Date

December 2010

Volume

12

Issue

14-15

Start / End Page

1111 / 1119

Location

France

Related Subject Headings

  • Virus Diseases
  • T-Lymphocytes
  • Microbiology
  • Interleukins
  • Helminthiasis
  • Chronic Disease
  • 3204 Immunology
  • 3107 Microbiology
  • 1108 Medical Microbiology
  • 1107 Immunology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Yi, J. S., Cox, M. A., & Zajac, A. J. (2010). Interleukin-21: a multifunctional regulator of immunity to infections. Microbes Infect, 12(14–15), 1111–1119. https://doi.org/10.1016/j.micinf.2010.08.008
Yi, John S., Maureen A. Cox, and Allan J. Zajac. “Interleukin-21: a multifunctional regulator of immunity to infections.Microbes Infect 12, no. 14–15 (December 2010): 1111–19. https://doi.org/10.1016/j.micinf.2010.08.008.
Yi JS, Cox MA, Zajac AJ. Interleukin-21: a multifunctional regulator of immunity to infections. Microbes Infect. 2010 Dec;12(14–15):1111–9.
Yi, John S., et al. “Interleukin-21: a multifunctional regulator of immunity to infections.Microbes Infect, vol. 12, no. 14–15, Dec. 2010, pp. 1111–19. Pubmed, doi:10.1016/j.micinf.2010.08.008.
Yi JS, Cox MA, Zajac AJ. Interleukin-21: a multifunctional regulator of immunity to infections. Microbes Infect. 2010 Dec;12(14–15):1111–1119.
Journal cover image

Published In

Microbes Infect

DOI

EISSN

1769-714X

Publication Date

December 2010

Volume

12

Issue

14-15

Start / End Page

1111 / 1119

Location

France

Related Subject Headings

  • Virus Diseases
  • T-Lymphocytes
  • Microbiology
  • Interleukins
  • Helminthiasis
  • Chronic Disease
  • 3204 Immunology
  • 3107 Microbiology
  • 1108 Medical Microbiology
  • 1107 Immunology