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Treatment for meibomian gland dysfunction and dry eye symptoms with a single-dose vectored thermal pulsation: a review.

Publication ,  Journal Article
Blackie, CA; Carlson, AN; Korb, DR
Published in: Curr Opin Ophthalmol
July 2015

PURPOSE OF REVIEW: Meibomian gland dysfunction (MGD) is understood to be a highly prevalent, chronic progressive disease and the leading cause of dry eye. All available published peer-reviewed results of the novel vectored thermal pulsation therapy for patients with MGD are investigated. RECENT FINDINGS: The PubMed and meeting abstract search revealed a total of 31 peer-reviewed reports on vectored thermal pulsation therapy at the time of the search (eight manuscripts and 23 meeting abstracts). All manuscripts evidence a significant increase in meibomian gland function (∼3×) and symptom improvement post a single 12-min treatment. Additional reported objective measures such as osmolarity, tear break-up time, or lipid layer thickness also increased as a result of the therapy; however, not all findings were statistically significant. The randomized controlled studies evidence sustained gland function and symptom relief lasting out to 12 months. The uncontrolled case series evidence significantly longer duration of effect. SUMMARY: A single 12 minute vectored thermal pulsation treatment allows for reducing dry eye symptoms, improving meibomian gland function and other correlates of the ocular surface health.

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Published In

Curr Opin Ophthalmol

DOI

EISSN

1531-7021

Publication Date

July 2015

Volume

26

Issue

4

Start / End Page

306 / 313

Location

United States

Related Subject Headings

  • Ophthalmology & Optometry
  • Meibomian Glands
  • Massage
  • Hyperthermia, Induced
  • Humans
  • Eyelid Diseases
  • Dry Eye Syndromes
  • 3212 Ophthalmology and optometry
  • 1113 Opthalmology and Optometry
 

Citation

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Blackie, C. A., Carlson, A. N., & Korb, D. R. (2015). Treatment for meibomian gland dysfunction and dry eye symptoms with a single-dose vectored thermal pulsation: a review. Curr Opin Ophthalmol, 26(4), 306–313. https://doi.org/10.1097/ICU.0000000000000165
Blackie, Caroline A., Alan N. Carlson, and Donald R. Korb. “Treatment for meibomian gland dysfunction and dry eye symptoms with a single-dose vectored thermal pulsation: a review.Curr Opin Ophthalmol 26, no. 4 (July 2015): 306–13. https://doi.org/10.1097/ICU.0000000000000165.
Blackie CA, Carlson AN, Korb DR. Treatment for meibomian gland dysfunction and dry eye symptoms with a single-dose vectored thermal pulsation: a review. Curr Opin Ophthalmol. 2015 Jul;26(4):306–13.
Blackie, Caroline A., et al. “Treatment for meibomian gland dysfunction and dry eye symptoms with a single-dose vectored thermal pulsation: a review.Curr Opin Ophthalmol, vol. 26, no. 4, July 2015, pp. 306–13. Pubmed, doi:10.1097/ICU.0000000000000165.
Blackie CA, Carlson AN, Korb DR. Treatment for meibomian gland dysfunction and dry eye symptoms with a single-dose vectored thermal pulsation: a review. Curr Opin Ophthalmol. 2015 Jul;26(4):306–313.

Published In

Curr Opin Ophthalmol

DOI

EISSN

1531-7021

Publication Date

July 2015

Volume

26

Issue

4

Start / End Page

306 / 313

Location

United States

Related Subject Headings

  • Ophthalmology & Optometry
  • Meibomian Glands
  • Massage
  • Hyperthermia, Induced
  • Humans
  • Eyelid Diseases
  • Dry Eye Syndromes
  • 3212 Ophthalmology and optometry
  • 1113 Opthalmology and Optometry