Metabolomics applied to the pancreatic islet.
Publication
, Journal Article
Gooding, JR; Jensen, MV; Newgard, CB
Published in: Arch Biochem Biophys
January 1, 2016
Metabolomics, the characterization of the set of small molecules in a biological system, is advancing research in multiple areas of islet biology. Measuring a breadth of metabolites simultaneously provides a broad perspective on metabolic changes as the islets respond dynamically to metabolic fuels, hormones, or environmental stressors. As a result, metabolomics has the potential to provide new mechanistic insights into islet physiology and pathophysiology. Here we summarize advances in our understanding of islet physiology and the etiologies of type-1 and type-2 diabetes gained from metabolomics studies.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Arch Biochem Biophys
DOI
EISSN
1096-0384
Publication Date
January 1, 2016
Volume
589
Start / End Page
120 / 130
Location
United States
Related Subject Headings
- Metabolomics
- Islets of Langerhans
- Humans
- Diabetes Mellitus, Type 2
- Diabetes Mellitus, Type 1
- Biochemistry & Molecular Biology
- Animals
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Gooding, J. R., Jensen, M. V., & Newgard, C. B. (2016). Metabolomics applied to the pancreatic islet. Arch Biochem Biophys, 589, 120–130. https://doi.org/10.1016/j.abb.2015.06.013
Gooding, Jessica R., Mette V. Jensen, and Christopher B. Newgard. “Metabolomics applied to the pancreatic islet.” Arch Biochem Biophys 589 (January 1, 2016): 120–30. https://doi.org/10.1016/j.abb.2015.06.013.
Gooding JR, Jensen MV, Newgard CB. Metabolomics applied to the pancreatic islet. Arch Biochem Biophys. 2016 Jan 1;589:120–30.
Gooding, Jessica R., et al. “Metabolomics applied to the pancreatic islet.” Arch Biochem Biophys, vol. 589, Jan. 2016, pp. 120–30. Pubmed, doi:10.1016/j.abb.2015.06.013.
Gooding JR, Jensen MV, Newgard CB. Metabolomics applied to the pancreatic islet. Arch Biochem Biophys. 2016 Jan 1;589:120–130.
Published In
Arch Biochem Biophys
DOI
EISSN
1096-0384
Publication Date
January 1, 2016
Volume
589
Start / End Page
120 / 130
Location
United States
Related Subject Headings
- Metabolomics
- Islets of Langerhans
- Humans
- Diabetes Mellitus, Type 2
- Diabetes Mellitus, Type 1
- Biochemistry & Molecular Biology
- Animals
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology