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SU-D-213-05: Design, Evaluation and First Applications of a Off-Site State-Of-The-Art 3D Dosimetry System.

Publication ,  Journal Article
Malcolm, J; Mein, S; McNiven, A; Letourneau, D; Oldham, M
Published in: Med Phys
June 2015

PURPOSE: To design, construct and commission a prototype in-house three dimensional (3D) dose verification system for stereotatic body radiotherapy (SBRT) verification at an off-site partner institution. To investigate the potential of this system to achieve sufficient performance (1mm resolution, 3% noise, within 3% of true dose reading) for SBRT verification. METHODS: The system was designed utilizing a parallel ray geometry instigated by precision telecentric lenses and an LED 630nm light source. Using a radiochromic dosimeter, a 3D dosimetric comparison with our gold-standard system and treatment planning software (Eclipse) was done for a four-field box treatment, under gamma passing criteria of 3%/3mm/10% dose threshold. Post off-site installation, deviations in the system's dose readout performance was assessed by rescanning the four-field box irradiated dosimeter and using line-profiles to compare on-site and off-site mean and noise levels in four distinct dose regions. As a final step, an end-to-end test of the system was completed at the off-site location, including CT-simulation, irradiation of the dosimeter and a 3D dosimetric comparison of the planned (Pinnacle(3)) to delivered dose for a spinal SBRT treatment(12 Gy per fraction). RESULTS: The noise level in the high and medium dose regions of the four field box treatment was relatively 5% pre and post installation. This reflects the reduction in positional uncertainty through the new design. This At 1mm dose voxels, the gamma pass rates(3%,3mm) for our in-house gold standard system and the off-site system were comparable at 95.8% and 93.2% respectively. CONCLUSION: This work will describe the end-to-end process and results of designing, installing, and commissioning a state-of-the-art 3D dosimetry system created for verification of advanced radiation treatments including spinal radiosurgery.

Duke Scholars

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

June 2015

Volume

42

Issue

6

Start / End Page

3207

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • 5105 Medical and biological physics
  • 4003 Biomedical engineering
  • 1112 Oncology and Carcinogenesis
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Malcolm, J., Mein, S., McNiven, A., Letourneau, D., & Oldham, M. (2015). SU-D-213-05: Design, Evaluation and First Applications of a Off-Site State-Of-The-Art 3D Dosimetry System. Med Phys, 42(6), 3207. https://doi.org/10.1118/1.4923857
Malcolm, J., S. Mein, A. McNiven, D. Letourneau, and M. Oldham. “SU-D-213-05: Design, Evaluation and First Applications of a Off-Site State-Of-The-Art 3D Dosimetry System.Med Phys 42, no. 6 (June 2015): 3207. https://doi.org/10.1118/1.4923857.
Malcolm J, Mein S, McNiven A, Letourneau D, Oldham M. SU-D-213-05: Design, Evaluation and First Applications of a Off-Site State-Of-The-Art 3D Dosimetry System. Med Phys. 2015 Jun;42(6):3207.
Malcolm, J., et al. “SU-D-213-05: Design, Evaluation and First Applications of a Off-Site State-Of-The-Art 3D Dosimetry System.Med Phys, vol. 42, no. 6, June 2015, p. 3207. Pubmed, doi:10.1118/1.4923857.
Malcolm J, Mein S, McNiven A, Letourneau D, Oldham M. SU-D-213-05: Design, Evaluation and First Applications of a Off-Site State-Of-The-Art 3D Dosimetry System. Med Phys. 2015 Jun;42(6):3207.

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

June 2015

Volume

42

Issue

6

Start / End Page

3207

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • 5105 Medical and biological physics
  • 4003 Biomedical engineering
  • 1112 Oncology and Carcinogenesis
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences