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The balance of the evidence on acid-base homeostasis and progression of chronic kidney disease.

Publication ,  Journal Article
Scialla, JJ
Published in: Kidney Int
July 2015

Normalization of acid-base homeostasis in chronic kidney disease (CKD) holds promise for mitigating disease progression, but whether efforts should focus on patients with low serum bicarbonate or high dietary acid load is unknown. Vallet et al. report that low urinary ammonia excretion independently associates with increased progression in moderate CKD. Whether this finding implicates differences in endogenous acid production or the ability to excrete an acid load in the pathogenesis of progression requires further study.

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Published In

Kidney Int

DOI

EISSN

1523-1755

Publication Date

July 2015

Volume

88

Issue

1

Start / End Page

9 / 11

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Renal Insufficiency, Chronic
  • Male
  • Humans
  • Female
  • Carbon Dioxide
  • Ammonia
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

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ICMJE
MLA
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Scialla, J. J. (2015). The balance of the evidence on acid-base homeostasis and progression of chronic kidney disease. Kidney Int, 88(1), 9–11. https://doi.org/10.1038/ki.2015.87
Scialla, Julia J. “The balance of the evidence on acid-base homeostasis and progression of chronic kidney disease.Kidney Int 88, no. 1 (July 2015): 9–11. https://doi.org/10.1038/ki.2015.87.
Scialla, Julia J. “The balance of the evidence on acid-base homeostasis and progression of chronic kidney disease.Kidney Int, vol. 88, no. 1, July 2015, pp. 9–11. Pubmed, doi:10.1038/ki.2015.87.
Journal cover image

Published In

Kidney Int

DOI

EISSN

1523-1755

Publication Date

July 2015

Volume

88

Issue

1

Start / End Page

9 / 11

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Renal Insufficiency, Chronic
  • Male
  • Humans
  • Female
  • Carbon Dioxide
  • Ammonia
  • 3202 Clinical sciences
  • 1103 Clinical Sciences