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Recent scientific advances in leiomyoma (uterine fibroids) research facilitates better understanding and management.

Publication ,  Journal Article
Taylor, DK; Holthouser, K; Segars, JH; Leppert, PC
Published in: F1000Res
2015

Uterine leiomyomas (fibroids) are the most prevalent medical problem of the female reproductive tract, but there are few non-surgical treatment options. Although many advances in the understanding of the molecular components of these tumors have occurred over the past five years, an effective pharmaceutical approach remains elusive. Further, there is currently no clinical method to distinguish a benign uterine leiomyoma from a malignant leiomyosarcoma prior to treatment, a pressing need given concerns about the use of the power morcellator for minimally invasive surgery. This paper reviews current studies regarding the molecular biology of uterine fibroids, discusses non-surgical approaches and suggests new cutting-edge therapeutic and diagnostic approaches.

Duke Scholars

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Published In

F1000Res

DOI

ISSN

2046-1402

Publication Date

2015

Volume

4

Issue

F1000 Faculty Rev

Start / End Page

183

Location

England

Related Subject Headings

  • 1112 Oncology and Carcinogenesis
  • 1103 Clinical Sciences
  • 0601 Biochemistry and Cell Biology
 

Citation

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Taylor, D. K., Holthouser, K., Segars, J. H., & Leppert, P. C. (2015). Recent scientific advances in leiomyoma (uterine fibroids) research facilitates better understanding and management. F1000Res, 4(F1000 Faculty Rev), 183. https://doi.org/10.12688/f1000research.6189.1
Taylor, Darlene K., Kristine Holthouser, James H. Segars, and Phyllis C. Leppert. “Recent scientific advances in leiomyoma (uterine fibroids) research facilitates better understanding and management.F1000Res 4, no. F1000 Faculty Rev (2015): 183. https://doi.org/10.12688/f1000research.6189.1.
Taylor DK, Holthouser K, Segars JH, Leppert PC. Recent scientific advances in leiomyoma (uterine fibroids) research facilitates better understanding and management. F1000Res. 2015;4(F1000 Faculty Rev):183.
Taylor, Darlene K., et al. “Recent scientific advances in leiomyoma (uterine fibroids) research facilitates better understanding and management.F1000Res, vol. 4, no. F1000 Faculty Rev, 2015, p. 183. Pubmed, doi:10.12688/f1000research.6189.1.
Taylor DK, Holthouser K, Segars JH, Leppert PC. Recent scientific advances in leiomyoma (uterine fibroids) research facilitates better understanding and management. F1000Res. 2015;4(F1000 Faculty Rev):183.

Published In

F1000Res

DOI

ISSN

2046-1402

Publication Date

2015

Volume

4

Issue

F1000 Faculty Rev

Start / End Page

183

Location

England

Related Subject Headings

  • 1112 Oncology and Carcinogenesis
  • 1103 Clinical Sciences
  • 0601 Biochemistry and Cell Biology