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The nature of immune responses to urinary tract infections.

Publication ,  Journal Article
Abraham, SN; Miao, Y
Published in: Nat Rev Immunol
October 2015

The urinary tract is constantly exposed to microorganisms that inhabit the gastrointestinal tract, but generally the urinary tract resists infection by gut microorganisms. This resistance to infection is mainly ascribed to the versatility of the innate immune defences in the urinary tract, as the adaptive immune responses are limited particularly when only the lower urinary tract is infected. In recent years, as the strengths and weaknesses of the immune system of the urinary tract have emerged and as the virulence attributes of uropathogens are recognized, several potentially effective and unconventional strategies to contain or prevent urinary tract infections have emerged.

Duke Scholars

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Published In

Nat Rev Immunol

DOI

EISSN

1474-1741

Publication Date

October 2015

Volume

15

Issue

10

Start / End Page

655 / 663

Location

England

Related Subject Headings

  • Virulence
  • Urinary Tract Infections
  • Models, Immunological
  • Immunology
  • Immunity, Innate
  • Humans
  • Host-Pathogen Interactions
  • Escherichia coli
  • Bacterial Infections
  • Bacteria
 

Citation

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Abraham, S. N., & Miao, Y. (2015). The nature of immune responses to urinary tract infections. Nat Rev Immunol, 15(10), 655–663. https://doi.org/10.1038/nri3887
Abraham, Soman N., and Yuxuan Miao. “The nature of immune responses to urinary tract infections.Nat Rev Immunol 15, no. 10 (October 2015): 655–63. https://doi.org/10.1038/nri3887.
Abraham SN, Miao Y. The nature of immune responses to urinary tract infections. Nat Rev Immunol. 2015 Oct;15(10):655–63.
Abraham, Soman N., and Yuxuan Miao. “The nature of immune responses to urinary tract infections.Nat Rev Immunol, vol. 15, no. 10, Oct. 2015, pp. 655–63. Pubmed, doi:10.1038/nri3887.
Abraham SN, Miao Y. The nature of immune responses to urinary tract infections. Nat Rev Immunol. 2015 Oct;15(10):655–663.

Published In

Nat Rev Immunol

DOI

EISSN

1474-1741

Publication Date

October 2015

Volume

15

Issue

10

Start / End Page

655 / 663

Location

England

Related Subject Headings

  • Virulence
  • Urinary Tract Infections
  • Models, Immunological
  • Immunology
  • Immunity, Innate
  • Humans
  • Host-Pathogen Interactions
  • Escherichia coli
  • Bacterial Infections
  • Bacteria