Lab-on-a-disk immunoassay for ocular diagnostics
Publication
, Conference
Walsh, DI; Murthy, SK; Hahn, PS; Jaffe, GJ; Sommer, GJ; Schaff, UY
Published in: Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
December 2, 2014
Monitoring of angiogenic cytokines in the eyes of patients with diabetic retinopathy (DR) and age-related macular degeneration (AMD) is crucial to confirm efficacy of treatment. We present a novel 'lab-on-a-disk' immunoassay for monitoring vascular endothelial growth factor in the eye with potential for deployment at the ophthalmologist's office as a point-of-care diagnostic. Using rudimentary sedimentation principles, the immunoassay can be completed in a two-step method within 16-18 minutes. The platform is comparable in sensitivity to conventional ELISA. Adoption of this platform at the point-of-care will facilitate accurate dosing of anti-angiogenic medication used to treat DR and AMD as well as identify non-responders.
Duke Scholars
Published In
Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
DOI
EISSN
2160-7001
ISSN
1071-121X
ISBN
9781479937288
Publication Date
December 2, 2014
Volume
2014-December
Citation
APA
Chicago
ICMJE
MLA
NLM
Walsh, D. I., Murthy, S. K., Hahn, P. S., Jaffe, G. J., Sommer, G. J., & Schaff, U. Y. (2014). Lab-on-a-disk immunoassay for ocular diagnostics. In Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC (Vol. 2014-December). https://doi.org/10.1109/NEBEC.2014.6972966
Walsh, D. I., S. K. Murthy, P. S. Hahn, G. J. Jaffe, G. J. Sommer, and U. Y. Schaff. “Lab-on-a-disk immunoassay for ocular diagnostics.” In Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC, Vol. 2014-December, 2014. https://doi.org/10.1109/NEBEC.2014.6972966.
Walsh DI, Murthy SK, Hahn PS, Jaffe GJ, Sommer GJ, Schaff UY. Lab-on-a-disk immunoassay for ocular diagnostics. In: Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC. 2014.
Walsh, D. I., et al. “Lab-on-a-disk immunoassay for ocular diagnostics.” Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC, vol. 2014-December, 2014. Scopus, doi:10.1109/NEBEC.2014.6972966.
Walsh DI, Murthy SK, Hahn PS, Jaffe GJ, Sommer GJ, Schaff UY. Lab-on-a-disk immunoassay for ocular diagnostics. Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC. 2014.
Published In
Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
DOI
EISSN
2160-7001
ISSN
1071-121X
ISBN
9781479937288
Publication Date
December 2, 2014
Volume
2014-December