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Vertebrate Reproduction.

Publication ,  Journal Article
Kornbluth, S; Fissore, R
Published in: Cold Spring Harbor perspectives in biology
October 2015

Vertebrate reproduction requires a myriad of precisely orchestrated events-in particular, the maternal production of oocytes, the paternal production of sperm, successful fertilization, and initiation of early embryonic cell divisions. These processes are governed by a host of signaling pathways. Protein kinase and phosphatase signaling pathways involving Mos, CDK1, RSK, and PP2A regulate meiosis during maturation of the oocyte. Steroid signals-specifically testosterone-regulate spermatogenesis, as does signaling by G-protein-coupled hormone receptors. Finally, calcium signaling is essential for both sperm motility and fertilization. Altogether, this signaling symphony ensures the production of viable offspring, offering a chance of genetic immortality.

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Published In

Cold Spring Harbor perspectives in biology

DOI

EISSN

1943-0264

ISSN

1943-0264

Publication Date

October 2015

Volume

7

Issue

10

Start / End Page

a006064

Related Subject Headings

  • Zygote
  • Vertebrates
  • Stem Cells
  • Spermatozoa
  • Spermatogenesis
  • Sperm Capacitation
  • Signal Transduction
  • Reproduction
  • Oocytes
  • Meiosis
 

Citation

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Kornbluth, S., & Fissore, R. (2015). Vertebrate Reproduction. Cold Spring Harbor Perspectives in Biology, 7(10), a006064. https://doi.org/10.1101/cshperspect.a006064
Kornbluth, Sally, and Rafael Fissore. “Vertebrate Reproduction.Cold Spring Harbor Perspectives in Biology 7, no. 10 (October 2015): a006064. https://doi.org/10.1101/cshperspect.a006064.
Kornbluth S, Fissore R. Vertebrate Reproduction. Cold Spring Harbor perspectives in biology. 2015 Oct;7(10):a006064.
Kornbluth, Sally, and Rafael Fissore. “Vertebrate Reproduction.Cold Spring Harbor Perspectives in Biology, vol. 7, no. 10, Oct. 2015, p. a006064. Epmc, doi:10.1101/cshperspect.a006064.
Kornbluth S, Fissore R. Vertebrate Reproduction. Cold Spring Harbor perspectives in biology. 2015 Oct;7(10):a006064.

Published In

Cold Spring Harbor perspectives in biology

DOI

EISSN

1943-0264

ISSN

1943-0264

Publication Date

October 2015

Volume

7

Issue

10

Start / End Page

a006064

Related Subject Headings

  • Zygote
  • Vertebrates
  • Stem Cells
  • Spermatozoa
  • Spermatogenesis
  • Sperm Capacitation
  • Signal Transduction
  • Reproduction
  • Oocytes
  • Meiosis