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The National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA): A Multisite Study of Adolescent Development and Substance Use.

Publication ,  Journal Article
Brown, SA; Brumback, T; Tomlinson, K; Cummins, K; Thompson, WK; Nagel, BJ; De Bellis, MD; Hooper, SR; Clark, DB; Chung, T; Hasler, BP; Chu, W ...
Published in: Journal of studies on alcohol and drugs
November 2015

During adolescence, neurobiological maturation occurs concurrently with social and interpersonal changes, including the initiation of alcohol and other substance use. The National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA) is designed to disentangle the complex relationships between onset, escalation, and desistance of alcohol use and changes in neurocognitive functioning and neuromaturation.A sample of 831 youth, ages 12-21 years, was recruited at five sites across the United States, oversampling those at risk for alcohol use problems. Most (83%) had limited or no history of alcohol or other drug use, and a smaller portion (17%) exceeded drinking thresholds. A comprehensive assessment of biological development, family background, psychiatric symptomatology, and neuropsychological functioning-in addition to anatomical, diffusion, and functional brain magnetic resonance imaging-was completed at baseline.The NCANDA sample of youth is nationally representative of sex and racial/ethnic groups. More than 50% have at least one risk characteristic for subsequent heavy drinking (e.g., family history, internalizing or externalizing symptoms). As expected, those who exceeded drinking thresholds (n = 139) differ from those who did not (n = 692) on identified factors associated with early alcohol use and problems.NCANDA successfully recruited a large sample of adolescents and comprehensively assessed psychosocial functioning across multiple domains. Based on the sample's risk profile, NCANDA is well positioned to capture the transition into drinking and alcohol problems in a large portion of the cohort, as well as to help disentangle the associations between alcohol use, neurobiological maturation, and neurocognitive development and functioning.

Published In

Journal of studies on alcohol and drugs

DOI

EISSN

1938-4114

ISSN

1937-1888

Publication Date

November 2015

Volume

76

Issue

6

Start / End Page

895 / 908

Related Subject Headings

  • Young Adult
  • United States
  • Substance-Related Disorders
  • Substance Abuse
  • Male
  • Humans
  • Female
  • Child
  • Alcoholism
  • Alcohol Drinking
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Brown, S. A., Brumback, T., Tomlinson, K., Cummins, K., Thompson, W. K., Nagel, B. J., … Tapert, S. F. (2015). The National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA): A Multisite Study of Adolescent Development and Substance Use. Journal of Studies on Alcohol and Drugs, 76(6), 895–908. https://doi.org/10.15288/jsad.2015.76.895
Brown, Sandra A., Ty Brumback, Kristin Tomlinson, Kevin Cummins, Wesley K. Thompson, Bonnie J. Nagel, Michael D. De Bellis, et al. “The National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA): A Multisite Study of Adolescent Development and Substance Use.Journal of Studies on Alcohol and Drugs 76, no. 6 (November 2015): 895–908. https://doi.org/10.15288/jsad.2015.76.895.
Brown SA, Brumback T, Tomlinson K, Cummins K, Thompson WK, Nagel BJ, et al. The National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA): A Multisite Study of Adolescent Development and Substance Use. Journal of studies on alcohol and drugs. 2015 Nov;76(6):895–908.
Brown, Sandra A., et al. “The National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA): A Multisite Study of Adolescent Development and Substance Use.Journal of Studies on Alcohol and Drugs, vol. 76, no. 6, Nov. 2015, pp. 895–908. Epmc, doi:10.15288/jsad.2015.76.895.
Brown SA, Brumback T, Tomlinson K, Cummins K, Thompson WK, Nagel BJ, De Bellis MD, Hooper SR, Clark DB, Chung T, Hasler BP, Colrain IM, Baker FC, Prouty D, Pfefferbaum A, Sullivan EV, Pohl KM, Rohlfing T, Nichols BN, Chu W, Tapert SF. The National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA): A Multisite Study of Adolescent Development and Substance Use. Journal of studies on alcohol and drugs. 2015 Nov;76(6):895–908.

Published In

Journal of studies on alcohol and drugs

DOI

EISSN

1938-4114

ISSN

1937-1888

Publication Date

November 2015

Volume

76

Issue

6

Start / End Page

895 / 908

Related Subject Headings

  • Young Adult
  • United States
  • Substance-Related Disorders
  • Substance Abuse
  • Male
  • Humans
  • Female
  • Child
  • Alcoholism
  • Alcohol Drinking