Surrogate markers in antiangiogenesis clinical trials.
Publication
, Journal Article
Davis, DW; McConkey, DJ; Abbruzzese, JL; Herbst, RS
Published in: Br J Cancer
July 7, 2003
Novel antiangiogenic agents currently being developed may ultimately be more effective against solid tumours and less toxic than cytotoxic chemotherapy. As a result of the early clinical trials of angiogenesis inhibitors, investigators are beginning to appreciate the complexity of targeting angiogenesis and the realisation that developing clinically useful antiangiogenic therapy will be more challenging than originally thought. It is now apparent that new methods and surrogate markers to assess these agents' biological activity are crucial for their successful development. This review summarises the currently available clinical data on the development of surrogate markers of angiogenesis inhibitors.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Br J Cancer
DOI
ISSN
0007-0920
Publication Date
July 7, 2003
Volume
89
Issue
1
Start / End Page
8 / 14
Location
England
Related Subject Headings
- Treatment Outcome
- Oncology & Carcinogenesis
- Neoplasms
- Microscopy, Confocal
- Humans
- Clinical Trials as Topic
- Biopsy
- Biomarkers, Tumor
- Angiogenesis Inhibitors
- 3211 Oncology and carcinogenesis
Citation
APA
Chicago
ICMJE
MLA
NLM
Davis, D. W., McConkey, D. J., Abbruzzese, J. L., & Herbst, R. S. (2003). Surrogate markers in antiangiogenesis clinical trials. Br J Cancer, 89(1), 8–14. https://doi.org/10.1038/sj.bjc.6601035
Davis, D. W., D. J. McConkey, J. L. Abbruzzese, and R. S. Herbst. “Surrogate markers in antiangiogenesis clinical trials.” Br J Cancer 89, no. 1 (July 7, 2003): 8–14. https://doi.org/10.1038/sj.bjc.6601035.
Davis DW, McConkey DJ, Abbruzzese JL, Herbst RS. Surrogate markers in antiangiogenesis clinical trials. Br J Cancer. 2003 Jul 7;89(1):8–14.
Davis, D. W., et al. “Surrogate markers in antiangiogenesis clinical trials.” Br J Cancer, vol. 89, no. 1, July 2003, pp. 8–14. Pubmed, doi:10.1038/sj.bjc.6601035.
Davis DW, McConkey DJ, Abbruzzese JL, Herbst RS. Surrogate markers in antiangiogenesis clinical trials. Br J Cancer. 2003 Jul 7;89(1):8–14.
Published In
Br J Cancer
DOI
ISSN
0007-0920
Publication Date
July 7, 2003
Volume
89
Issue
1
Start / End Page
8 / 14
Location
England
Related Subject Headings
- Treatment Outcome
- Oncology & Carcinogenesis
- Neoplasms
- Microscopy, Confocal
- Humans
- Clinical Trials as Topic
- Biopsy
- Biomarkers, Tumor
- Angiogenesis Inhibitors
- 3211 Oncology and carcinogenesis