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Navigating MRI-TRUS fusion biopsy: optimizing the process and avoiding technical pitfalls.

Publication ,  Journal Article
Tay, KJ; Gupta, RT; Rastinehad, AR; Tsivian, E; Freedland, SJ; Moul, JW; Polascik, TJ
Published in: Expert Rev Anticancer Ther
2016

Multi-parametric MRI (mpMRI) is widely used in the detection and characterization of clinically- significant prostate cancer. MRI-TRUS (trans-rectal ultrasound) fusion biopsy is an in-office procedure that promises to empower urologists to successfully target these MRI-visible lesions for histological confirmation. We describe the moving parts in the process and discuss methods to optimize biopsy outcomes. mpMRI is highly technical and reader-dependent. The acquisition of US images to generate a valid 3D US model and subsequent registration and fusion requires the urologist to attain equilibrium of probe position and pressure to achieve maximum registration accuracy. Environmental, medical and engineering measures can be undertaken to improve targeting accuracy. The art and skill of 'hitting' a visual target involves real-time recognition and adjustment for potential errors/ mis-registration in the fusion guide. A multi-disciplinary team effort is critical to improve all steps of the procedure.

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Published In

Expert Rev Anticancer Ther

DOI

EISSN

1744-8328

Publication Date

2016

Volume

16

Issue

3

Start / End Page

303 / 311

Location

England

Related Subject Headings

  • Ultrasonography, Interventional
  • Prostatic Neoplasms
  • Oncology & Carcinogenesis
  • Male
  • Magnetic Resonance Imaging
  • Image-Guided Biopsy
  • Humans
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
 

Citation

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Tay, K. J., Gupta, R. T., Rastinehad, A. R., Tsivian, E., Freedland, S. J., Moul, J. W., & Polascik, T. J. (2016). Navigating MRI-TRUS fusion biopsy: optimizing the process and avoiding technical pitfalls. Expert Rev Anticancer Ther, 16(3), 303–311. https://doi.org/10.1586/14737140.2016.1131155
Tay, Kae Jack, Rajan T. Gupta, Ardeshir R. Rastinehad, Efrat Tsivian, Stephen J. Freedland, Judd W. Moul, and Thomas J. Polascik. “Navigating MRI-TRUS fusion biopsy: optimizing the process and avoiding technical pitfalls.Expert Rev Anticancer Ther 16, no. 3 (2016): 303–11. https://doi.org/10.1586/14737140.2016.1131155.
Tay KJ, Gupta RT, Rastinehad AR, Tsivian E, Freedland SJ, Moul JW, et al. Navigating MRI-TRUS fusion biopsy: optimizing the process and avoiding technical pitfalls. Expert Rev Anticancer Ther. 2016;16(3):303–11.
Tay, Kae Jack, et al. “Navigating MRI-TRUS fusion biopsy: optimizing the process and avoiding technical pitfalls.Expert Rev Anticancer Ther, vol. 16, no. 3, 2016, pp. 303–11. Pubmed, doi:10.1586/14737140.2016.1131155.
Tay KJ, Gupta RT, Rastinehad AR, Tsivian E, Freedland SJ, Moul JW, Polascik TJ. Navigating MRI-TRUS fusion biopsy: optimizing the process and avoiding technical pitfalls. Expert Rev Anticancer Ther. 2016;16(3):303–311.
Journal cover image

Published In

Expert Rev Anticancer Ther

DOI

EISSN

1744-8328

Publication Date

2016

Volume

16

Issue

3

Start / End Page

303 / 311

Location

England

Related Subject Headings

  • Ultrasonography, Interventional
  • Prostatic Neoplasms
  • Oncology & Carcinogenesis
  • Male
  • Magnetic Resonance Imaging
  • Image-Guided Biopsy
  • Humans
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis