Phosphate modified analogues of 5'O-phosphorylated 2', 3'-dldeoxynucleosides: Synthesis and Anti-HIV activity
Publication
, Journal Article
Riggs, RM; Comber, RN; Montgomery, JA; Secrist, JA
Published in: Nucleosides and Nucleotides
January 1, 1989
Phosphonate analogues of 5'-0-phosphoryl-2'3'-dideoxyribofuranosyl adenine, cytosine, hypoxanthine and thymine were synthesized. The hypoxanthine and thymine analogues were inactive against HIV induced cytopathy in the CEM-4 T-cell lines. The 2'3'-ddC and 2', 3'-ddA analogues were marginally active. © 1989, Taylor & Francis Group, LLC. All rights reserved.
Duke Scholars
Published In
Nucleosides and Nucleotides
DOI
ISSN
0732-8311
Publication Date
January 1, 1989
Volume
8
Issue
5-6
Start / End Page
1119 / 1120
Related Subject Headings
- Organic Chemistry
- 0601 Biochemistry and Cell Biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Riggs, R. M., Comber, R. N., Montgomery, J. A., & Secrist, J. A. (1989). Phosphate modified analogues of 5'O-phosphorylated 2', 3'-dldeoxynucleosides: Synthesis and Anti-HIV activity. Nucleosides and Nucleotides, 8(5–6), 1119–1120. https://doi.org/10.1080/07328318908054303
Riggs, R. M., R. N. Comber, J. A. Montgomery, and J. A. Secrist. “Phosphate modified analogues of 5'O-phosphorylated 2', 3'-dldeoxynucleosides: Synthesis and Anti-HIV activity.” Nucleosides and Nucleotides 8, no. 5–6 (January 1, 1989): 1119–20. https://doi.org/10.1080/07328318908054303.
Riggs RM, Comber RN, Montgomery JA, Secrist JA. Phosphate modified analogues of 5'O-phosphorylated 2', 3'-dldeoxynucleosides: Synthesis and Anti-HIV activity. Nucleosides and Nucleotides. 1989 Jan 1;8(5–6):1119–20.
Riggs, R. M., et al. “Phosphate modified analogues of 5'O-phosphorylated 2', 3'-dldeoxynucleosides: Synthesis and Anti-HIV activity.” Nucleosides and Nucleotides, vol. 8, no. 5–6, Jan. 1989, pp. 1119–20. Scopus, doi:10.1080/07328318908054303.
Riggs RM, Comber RN, Montgomery JA, Secrist JA. Phosphate modified analogues of 5'O-phosphorylated 2', 3'-dldeoxynucleosides: Synthesis and Anti-HIV activity. Nucleosides and Nucleotides. 1989 Jan 1;8(5–6):1119–1120.
Published In
Nucleosides and Nucleotides
DOI
ISSN
0732-8311
Publication Date
January 1, 1989
Volume
8
Issue
5-6
Start / End Page
1119 / 1120
Related Subject Headings
- Organic Chemistry
- 0601 Biochemistry and Cell Biology