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Hypoplastic vagina, partial vaginal septum, and coexisting hypogonadotropic hypogonadism: An unusual case of primary amenorrhea

Publication ,  Journal Article
Barker, NM; Prinz, D; Hurd, WW; Mahajan, ST; Bedaiwy, MA
Published in: Journal of Gynecologic Surgery
February 1, 2013

Background: Diagnosing a cause of primary amenorrhea can be challenging when multiple organ systems are affected. This article presents a patient with the rare combination of hypoplastic vagina, partial vaginal septum, and hypogonadotropic hypogonadism where surgical correction, hormone therapy, and vaginal dilation resulted in normal menstruation and sexual function. Case: A 34-year-old woman presented with primary amenorrhea and inability to have coitus. Examination revealed a 1.5-cm vagina ending in a blind pouch. Pelvic ultrasound confirmed the presence of bilateral ovaries, hypoplastic uterus, and cervix. No other renal or skeletal abnormalities were noted on magnetic resonance imaging. Laboratory evaluation was consistent with hypogonadotropic hypogonadism. Results: A combination of surgical excision of a partial vaginal septum, postoperative vaginal dilation, and hormonal therapy resulted in cyclic menstruation and acceptable sexual function. Conclusions: This case illustrates the difficulty of making a diagnosis in a patient with a combination of different causes of primary amenorrhea. Accurate and early diagnosis using appropriate imaging studies and endocrine profile is important to avoid treatment delay. © Mary Ann Liebert, Inc.

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Published In

Journal of Gynecologic Surgery

DOI

EISSN

1557-7724

ISSN

1042-4067

Publication Date

February 1, 2013

Volume

29

Issue

1

Start / End Page

19 / 22

Related Subject Headings

  • Obstetrics & Reproductive Medicine
 

Citation

APA
Chicago
ICMJE
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Barker, N. M., Prinz, D., Hurd, W. W., Mahajan, S. T., & Bedaiwy, M. A. (2013). Hypoplastic vagina, partial vaginal septum, and coexisting hypogonadotropic hypogonadism: An unusual case of primary amenorrhea. Journal of Gynecologic Surgery, 29(1), 19–22. https://doi.org/10.1089/gyn.2012.0068
Barker, N. M., D. Prinz, W. W. Hurd, S. T. Mahajan, and M. A. Bedaiwy. “Hypoplastic vagina, partial vaginal septum, and coexisting hypogonadotropic hypogonadism: An unusual case of primary amenorrhea.” Journal of Gynecologic Surgery 29, no. 1 (February 1, 2013): 19–22. https://doi.org/10.1089/gyn.2012.0068.
Barker NM, Prinz D, Hurd WW, Mahajan ST, Bedaiwy MA. Hypoplastic vagina, partial vaginal septum, and coexisting hypogonadotropic hypogonadism: An unusual case of primary amenorrhea. Journal of Gynecologic Surgery. 2013 Feb 1;29(1):19–22.
Barker, N. M., et al. “Hypoplastic vagina, partial vaginal septum, and coexisting hypogonadotropic hypogonadism: An unusual case of primary amenorrhea.” Journal of Gynecologic Surgery, vol. 29, no. 1, Feb. 2013, pp. 19–22. Scopus, doi:10.1089/gyn.2012.0068.
Barker NM, Prinz D, Hurd WW, Mahajan ST, Bedaiwy MA. Hypoplastic vagina, partial vaginal septum, and coexisting hypogonadotropic hypogonadism: An unusual case of primary amenorrhea. Journal of Gynecologic Surgery. 2013 Feb 1;29(1):19–22.
Journal cover image

Published In

Journal of Gynecologic Surgery

DOI

EISSN

1557-7724

ISSN

1042-4067

Publication Date

February 1, 2013

Volume

29

Issue

1

Start / End Page

19 / 22

Related Subject Headings

  • Obstetrics & Reproductive Medicine