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Psychosocial factors and risk of hypertension: the Coronary Artery Risk Development in Young Adults (CARDIA) study.

Publication ,  Journal Article
Yan, LL; Liu, K; Matthews, KA; Daviglus, ML; Ferguson, TF; Kiefe, CI
Published in: JAMA
October 2003

Although psychosocial factors are correlated, previous studies on risk factors for hypertension have typically examined psychosocial factors individually and have yielded inconsistent findings.To examine the role of psychosocial factors of time urgency/impatience (TUI), achievement striving/competitiveness (ASC), hostility, depression, and anxiety on long-term risk of hypertension. DESIGN, SETTING, AND STUDY POPULATION: A population-based, prospective, observational study using participant data from the Coronary Artery Risk Development in Young Adults (CARDIA) study. A total of 3308 black and white adults aged 18 to 30 years (when recruited in 1985 and 1986) from 4 US metropolitan areas and followed up through 2000 to 2001.Fifteen-year cumulative incidence of hypertension (systolic blood pressure of 140 mm Hg or higher, diastolic blood pressure of 90 mm Hg or higher, or taking antihypertensive medication).The incidence of hypertension at year 15 was 15% from baseline and 13.6% from year 5. After adjusting for the same set of hypertension risk factors and each of the psychosocial factors of TUI, ASC, hostility, depression, and anxiety in 5 separate logistic regression models, higher TUI and hostility were significantly associated with risk of developing hypertension at 15-year follow-up for the total sample. Compared with the lowest score group, the adjusted odds ratio (OR) for TUI was 1.51 (95% confidence interval [CI], 1.12-2.03) for a score of 1; 1.47 (95% CI, 1.08-2.02) for a score of 2; and 1.84 (95% CI, 1.29-2.62) for a score of 3 to 4 (P for trend =.001). Compared with the lowest quartile group, the adjusted OR for hostility was 1.06 (95% CI, 0.76-1.47) for quartile 2; 1.38 (95% CI, 1.00-1.91) for quartile 3; and 1.84 (95% CI, 1.33-2.54) for quartile 4 (P for trend <.001). No consistent patterns were found for ASC, depression, or anxiety. Race- and sex-specific analyses and multivariable models with simultaneous adjustment for all 5 psychosocial factors and other hypertension risk factors had generally similar results.Among young adults, TUI and hostility were associated with a dose-response increase in the long-term risk of hypertension.

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Published In

JAMA

DOI

EISSN

1538-3598

ISSN

0098-7484

Publication Date

October 2003

Volume

290

Issue

16

Start / End Page

2138 / 2148

Related Subject Headings

  • White People
  • Stress, Psychological
  • Risk Factors
  • Prospective Studies
  • Multivariate Analysis
  • Male
  • Longitudinal Studies
  • Logistic Models
  • Hypertension
  • Humans
 

Citation

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Chicago
ICMJE
MLA
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Yan, L. L., Liu, K., Matthews, K. A., Daviglus, M. L., Ferguson, T. F., & Kiefe, C. I. (2003). Psychosocial factors and risk of hypertension: the Coronary Artery Risk Development in Young Adults (CARDIA) study. JAMA, 290(16), 2138–2148. https://doi.org/10.1001/jama.290.16.2138
Yan, Lijing L., Kiang Liu, Karen A. Matthews, Martha L. Daviglus, T Freeman Ferguson, and Catarina I. Kiefe. “Psychosocial factors and risk of hypertension: the Coronary Artery Risk Development in Young Adults (CARDIA) study.JAMA 290, no. 16 (October 2003): 2138–48. https://doi.org/10.1001/jama.290.16.2138.
Yan LL, Liu K, Matthews KA, Daviglus ML, Ferguson TF, Kiefe CI. Psychosocial factors and risk of hypertension: the Coronary Artery Risk Development in Young Adults (CARDIA) study. JAMA. 2003 Oct;290(16):2138–48.
Yan, Lijing L., et al. “Psychosocial factors and risk of hypertension: the Coronary Artery Risk Development in Young Adults (CARDIA) study.JAMA, vol. 290, no. 16, Oct. 2003, pp. 2138–48. Epmc, doi:10.1001/jama.290.16.2138.
Yan LL, Liu K, Matthews KA, Daviglus ML, Ferguson TF, Kiefe CI. Psychosocial factors and risk of hypertension: the Coronary Artery Risk Development in Young Adults (CARDIA) study. JAMA. 2003 Oct;290(16):2138–2148.
Journal cover image

Published In

JAMA

DOI

EISSN

1538-3598

ISSN

0098-7484

Publication Date

October 2003

Volume

290

Issue

16

Start / End Page

2138 / 2148

Related Subject Headings

  • White People
  • Stress, Psychological
  • Risk Factors
  • Prospective Studies
  • Multivariate Analysis
  • Male
  • Longitudinal Studies
  • Logistic Models
  • Hypertension
  • Humans