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Effects of depression and anxiety improvement on adherence to medication and health behaviors in recently hospitalized cardiac patients.

Publication ,  Journal Article
Bauer, LK; Caro, MA; Beach, SR; Mastromauro, CA; Lenihan, E; Januzzi, JL; Huffman, JC
Published in: Am J Cardiol
May 1, 2012

Impaired adherence to medications and health behaviors may mediate the connection between psychiatric symptoms and mortality in cardiac patients. This study assessed the association between improvements in depression/anxiety and self-reported adherence to health behaviors in depressed cardiac patients in the 6 months after cardiac hospitalization. Data were analyzed from depressed patients on inpatient cardiac units who were hospitalized for acute coronary syndrome, heart failure, or arrhythmia and enrolled in a randomized trial of collaborative care depression management (n = 134 in primary analysis). Measurements of depression (Patient Health Questionnaire-9), anxiety (Hospital Anxiety and Depression Scale, Anxiety subscale), and adherence to secondary prevention behaviors (Medical Outcomes Study-Specific Adherence Scale items) were obtained at baseline, 6 weeks 12 weeks, and 6 months. The association between improvement in depression/anxiety and adherence was assessed by linear regression after accounting for the effects of multiple relevant covariates. At all time points improvement in the Patient Health Questionnaire-9 was significantly and independently associated with self-reported adherence to medications and secondary prevention behaviors. In contrast, improvement in the Hospital Anxiety and Depression Scale, Anxiety subscale was associated with improved adherence only at 6 weeks. In conclusion, in a cohort of depressed cardiac patients, improvement in depression was consistently and independently associated with superior self-reported adherence to medications and secondary prevention behaviors across a 6-month span, whereas improvement in anxiety was not.

Published In

Am J Cardiol

DOI

EISSN

1879-1913

Publication Date

May 1, 2012

Volume

109

Issue

9

Start / End Page

1266 / 1271

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Surveys and Questionnaires
  • Severity of Illness Index
  • Prospective Studies
  • Middle Aged
  • Medication Adherence
  • Male
  • Inpatients
  • Humans
  • Heart Diseases
 

Citation

APA
Chicago
ICMJE
MLA
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Bauer, L. K., Caro, M. A., Beach, S. R., Mastromauro, C. A., Lenihan, E., Januzzi, J. L., & Huffman, J. C. (2012). Effects of depression and anxiety improvement on adherence to medication and health behaviors in recently hospitalized cardiac patients. Am J Cardiol, 109(9), 1266–1271. https://doi.org/10.1016/j.amjcard.2011.12.017
Bauer, Leah K., Mario A. Caro, Scott R. Beach, Carol A. Mastromauro, Emma Lenihan, James L. Januzzi, and Jeff C. Huffman. “Effects of depression and anxiety improvement on adherence to medication and health behaviors in recently hospitalized cardiac patients.Am J Cardiol 109, no. 9 (May 1, 2012): 1266–71. https://doi.org/10.1016/j.amjcard.2011.12.017.
Bauer LK, Caro MA, Beach SR, Mastromauro CA, Lenihan E, Januzzi JL, et al. Effects of depression and anxiety improvement on adherence to medication and health behaviors in recently hospitalized cardiac patients. Am J Cardiol. 2012 May 1;109(9):1266–71.
Bauer, Leah K., et al. “Effects of depression and anxiety improvement on adherence to medication and health behaviors in recently hospitalized cardiac patients.Am J Cardiol, vol. 109, no. 9, May 2012, pp. 1266–71. Pubmed, doi:10.1016/j.amjcard.2011.12.017.
Bauer LK, Caro MA, Beach SR, Mastromauro CA, Lenihan E, Januzzi JL, Huffman JC. Effects of depression and anxiety improvement on adherence to medication and health behaviors in recently hospitalized cardiac patients. Am J Cardiol. 2012 May 1;109(9):1266–1271.
Journal cover image

Published In

Am J Cardiol

DOI

EISSN

1879-1913

Publication Date

May 1, 2012

Volume

109

Issue

9

Start / End Page

1266 / 1271

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Surveys and Questionnaires
  • Severity of Illness Index
  • Prospective Studies
  • Middle Aged
  • Medication Adherence
  • Male
  • Inpatients
  • Humans
  • Heart Diseases