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Frequency of transient reductions in left ventricular ejection fraction at rest in coronary artery disease.

Publication ,  Journal Article
Freeman, MR; de Yang, L; Langer, A; Foley, B; Armstrong, PW
Published in: Am J Cardiol
July 15, 1994

To determine the prevalence of decreases in left ventricular (LV) ejection fraction (EF) at rest in patients with coronary artery disease (CAD), including those with stable angina (n = 21), unstable angina (n = 13), and recent myocardial infarction (n = 11), continuous assessment of LV function for 162 +/- 136 minutes was performed using a new nuclear device. The results were compared with those of a group of normal subjects (n = 10) monitored for 80 +/- 28 minutes. Episodes of EF reduction of > 7% from baseline for a total duration of > 5% monitored time occurred in 0 of 10 normal subjects; episodes were more frequent in patients with stable angina (10 of 21, 48%; p = 0.01), with recent myocardial infarction (7 of 11, 64%; p = 0.004), and with unstable angina (11 of 13, 85%; p = 0.0001). The number of EF decreases per hour in patients after myocardial infarction (1.7 +/- 2.5 [SD]) and unstable angina (1.2 +/- 0.7) was significantly more frequent than in normal subjects (0.3 +/- 0.4), but was not different from that in patients with stable angina (0.8 +/- 1.0). The duration of the decrease in EF, expressed as minutes per hour of monitored time in normal subjects (0.7 +/- 1.0%), was significantly less than in patients with unstable angina (10 +/- 8%). Patients with stable angina (6 +/- 9%) and recent myocardial infarction (6 +/- 6%) were not significantly different from normal subjects.(ABSTRACT TRUNCATED AT 250 WORDS)

Duke Scholars

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

July 15, 1994

Volume

74

Issue

2

Start / End Page

137 / 143

Location

United States

Related Subject Headings

  • Ventricular Function, Left
  • Time Factors
  • Stroke Volume
  • Rest
  • Myocardial Infarction
  • Middle Aged
  • Male
  • Humans
  • Heart Rate
  • Gated Blood-Pool Imaging
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Freeman, M. R., de Yang, L., Langer, A., Foley, B., & Armstrong, P. W. (1994). Frequency of transient reductions in left ventricular ejection fraction at rest in coronary artery disease. Am J Cardiol, 74(2), 137–143. https://doi.org/10.1016/0002-9149(94)90086-8
Freeman, M. R., L. de Yang, A. Langer, B. Foley, and P. W. Armstrong. “Frequency of transient reductions in left ventricular ejection fraction at rest in coronary artery disease.Am J Cardiol 74, no. 2 (July 15, 1994): 137–43. https://doi.org/10.1016/0002-9149(94)90086-8.
Freeman MR, de Yang L, Langer A, Foley B, Armstrong PW. Frequency of transient reductions in left ventricular ejection fraction at rest in coronary artery disease. Am J Cardiol. 1994 Jul 15;74(2):137–43.
Freeman, M. R., et al. “Frequency of transient reductions in left ventricular ejection fraction at rest in coronary artery disease.Am J Cardiol, vol. 74, no. 2, July 1994, pp. 137–43. Pubmed, doi:10.1016/0002-9149(94)90086-8.
Freeman MR, de Yang L, Langer A, Foley B, Armstrong PW. Frequency of transient reductions in left ventricular ejection fraction at rest in coronary artery disease. Am J Cardiol. 1994 Jul 15;74(2):137–143.
Journal cover image

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

July 15, 1994

Volume

74

Issue

2

Start / End Page

137 / 143

Location

United States

Related Subject Headings

  • Ventricular Function, Left
  • Time Factors
  • Stroke Volume
  • Rest
  • Myocardial Infarction
  • Middle Aged
  • Male
  • Humans
  • Heart Rate
  • Gated Blood-Pool Imaging