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Fibromyalgia symptoms and medication requirements respond to parathyroidectomy.

Publication ,  Journal Article
Adkisson, CD; Yip, L; Armstrong, MJ; Stang, MT; Carty, SE; McCoy, KL
Published in: Surgery
December 2014

BACKGROUND: Fibromyalgia (FM), an ill-defined symptom complex, is characterized by musculoskeletal pain, headache, depression, fatigue, and cognitive decline, symptoms also seen commonly in primary hyperparathyroidism (PHP). Prevalence of concurrent PHP and FM and response to parathyroidectomy (PTX) of those with both conditions are unknown. METHODS: We reviewed prospective data of 4,000 patients with sporadic PHP who had PTX from 1995 to 2013 examining perioperative symptoms and medication usage for those with diagnosed FM. Cure was defined by normocalcemia at ≥ 6 months. RESULTS: Of 2,184 patients, 80 (4%) had a prior diagnosis of FM. Of evaluable FM patients, 97.3% had definitive cure of PHP. After PTX, 89% had improvement in ≥ 1 symptom attributed to FM, with improved cognition/memory most common (80%). Improvement in ≥ 2, ≥ 3, and ≥ 4 FM symptoms was appreciated by 71%, 43%, and 25%, respectively. Quality of life and wellness improved in >50%. Postoperative use of drugs prescribed for FM often improved or resolved (narcotics, 77%; anti-inflammatories, 74%; "FM-specific medications," 33%; antidepressants, 30%); 21% discontinued all FM medications postoperatively. CONCLUSION: FM is common in patients operated on for sporadic PHP. Of those with both conditions, after PTX 89% appreciate symptom response and 77% and 21% had a decrease in or discontinuation or medications, respectively. Before diagnosing FM, providers should exclude PHP, which is surgically correctable.

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Published In

Surgery

DOI

EISSN

1532-7361

Publication Date

December 2014

Volume

156

Issue

6

Start / End Page

1614 / 1620

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Surgery
  • Severity of Illness Index
  • Risk Assessment
  • Retrospective Studies
  • Parathyroidectomy
  • Pain, Postoperative
  • Pain Measurement
  • Middle Aged
  • Male
 

Citation

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Chicago
ICMJE
MLA
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Adkisson, C. D., Yip, L., Armstrong, M. J., Stang, M. T., Carty, S. E., & McCoy, K. L. (2014). Fibromyalgia symptoms and medication requirements respond to parathyroidectomy. Surgery, 156(6), 1614–1620. https://doi.org/10.1016/j.surg.2014.08.063
Adkisson, Cameron D., Linwah Yip, Michaele J. Armstrong, Michael T. Stang, Sally E. Carty, and Kelly L. McCoy. “Fibromyalgia symptoms and medication requirements respond to parathyroidectomy.Surgery 156, no. 6 (December 2014): 1614–20. https://doi.org/10.1016/j.surg.2014.08.063.
Adkisson CD, Yip L, Armstrong MJ, Stang MT, Carty SE, McCoy KL. Fibromyalgia symptoms and medication requirements respond to parathyroidectomy. Surgery. 2014 Dec;156(6):1614–20.
Adkisson, Cameron D., et al. “Fibromyalgia symptoms and medication requirements respond to parathyroidectomy.Surgery, vol. 156, no. 6, Dec. 2014, pp. 1614–20. Pubmed, doi:10.1016/j.surg.2014.08.063.
Adkisson CD, Yip L, Armstrong MJ, Stang MT, Carty SE, McCoy KL. Fibromyalgia symptoms and medication requirements respond to parathyroidectomy. Surgery. 2014 Dec;156(6):1614–1620.
Journal cover image

Published In

Surgery

DOI

EISSN

1532-7361

Publication Date

December 2014

Volume

156

Issue

6

Start / End Page

1614 / 1620

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Surgery
  • Severity of Illness Index
  • Risk Assessment
  • Retrospective Studies
  • Parathyroidectomy
  • Pain, Postoperative
  • Pain Measurement
  • Middle Aged
  • Male