Toward clinical genomics in everyday medicine: perspectives and recommendations.
Precision or personalized medicine through clinical genome and exome sequencing has been described by some as a revolution that could transform healthcare delivery, yet it is currently used in only a small fraction of patients, principally for the diagnosis of suspected Mendelian conditions and for targeting cancer treatments. Given the burden of illness in our society, it is of interest to ask how clinical genome and exome sequencing can be constructively integrated more broadly into the routine practice of medicine for the betterment of public health. In November 2014, 46 experts from academia, industry, policy and patient advocacy gathered in a conference sponsored by Illumina, Inc. to discuss this question, share viewpoints and propose recommendations. This perspective summarizes that work and identifies some of the obstacles and opportunities that must be considered in translating advances in genomics more widely into the practice of medicine.
Duke Scholars
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Related Subject Headings
- Reagent Kits, Diagnostic
- Precision Medicine
- Humans
- High-Throughput Nucleotide Sequencing
- Genomics
- Genome, Human
- Genetic Testing
- Delivery of Health Care
- 3202 Clinical sciences
- 1103 Clinical Sciences
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Reagent Kits, Diagnostic
- Precision Medicine
- Humans
- High-Throughput Nucleotide Sequencing
- Genomics
- Genome, Human
- Genetic Testing
- Delivery of Health Care
- 3202 Clinical sciences
- 1103 Clinical Sciences