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Antiplatelet Therapy in Percutaneous Coronary Intervention.

Publication ,  Journal Article
Fanaroff, AC; Rao, SV
Published in: Interv Cardiol Clin
April 2016

Platelets play a key role in mediating stent thrombosis, which is the major cause of ischemic events immediately after percutaneous coronary intervention (PCI). Antiplatelet therapy is therefore the cornerstone of antithrombotic therapy after PCI. However, the use of antiplatelet agents increases bleeding risk, with more potent antiplatelet agents further increasing bleeding risk. In the past 5 years, potent and fast-acting P2Y12 inhibitors have augmented the antiplatelet armamentarium available to interventional cardiologists. This article reviews the preclinical and clinical data surrounding these new agents, and discusses the significant questions and controversies that still exist regarding the optimal antiplatelet strategy.

Duke Scholars

Published In

Interv Cardiol Clin

DOI

EISSN

2211-7466

Publication Date

April 2016

Volume

5

Issue

2

Start / End Page

221 / 237

Location

Netherlands

Related Subject Headings

  • Thrombosis
  • Platelet Aggregation Inhibitors
  • Percutaneous Coronary Intervention
  • Humans
  • Blood Platelets
  • Angioplasty, Balloon, Coronary
  • Acute Coronary Syndrome
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Fanaroff, A. C., & Rao, S. V. (2016). Antiplatelet Therapy in Percutaneous Coronary Intervention. Interv Cardiol Clin, 5(2), 221–237. https://doi.org/10.1016/j.iccl.2015.12.007
Fanaroff, Alexander C., and Sunil V. Rao. “Antiplatelet Therapy in Percutaneous Coronary Intervention.Interv Cardiol Clin 5, no. 2 (April 2016): 221–37. https://doi.org/10.1016/j.iccl.2015.12.007.
Fanaroff AC, Rao SV. Antiplatelet Therapy in Percutaneous Coronary Intervention. Interv Cardiol Clin. 2016 Apr;5(2):221–37.
Fanaroff, Alexander C., and Sunil V. Rao. “Antiplatelet Therapy in Percutaneous Coronary Intervention.Interv Cardiol Clin, vol. 5, no. 2, Apr. 2016, pp. 221–37. Pubmed, doi:10.1016/j.iccl.2015.12.007.
Fanaroff AC, Rao SV. Antiplatelet Therapy in Percutaneous Coronary Intervention. Interv Cardiol Clin. 2016 Apr;5(2):221–237.
Journal cover image

Published In

Interv Cardiol Clin

DOI

EISSN

2211-7466

Publication Date

April 2016

Volume

5

Issue

2

Start / End Page

221 / 237

Location

Netherlands

Related Subject Headings

  • Thrombosis
  • Platelet Aggregation Inhibitors
  • Percutaneous Coronary Intervention
  • Humans
  • Blood Platelets
  • Angioplasty, Balloon, Coronary
  • Acute Coronary Syndrome