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The Ties that Bind (the Igh Locus).

Publication ,  Journal Article
Krangel, MS
Published in: Trends Genet
May 2016

Immunoglobulin heavy-chain locus V(D)J recombination requires a 3D chromatin organization which permits widely distributed variable (V) gene segments to contact distant diversity (D) and joining (J) gene segments. A recent study has identified key nodes in the locus interactome, paving the way for new molecular insights into how the locus is configured for recombination.

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Published In

Trends Genet

DOI

ISSN

0168-9525

Publication Date

May 2016

Volume

32

Issue

5

Start / End Page

253 / 255

Location

England

Related Subject Headings

  • VDJ Recombinases
  • Transcription, Genetic
  • Recombination, Genetic
  • Mice
  • Immunoglobulins
  • Humans
  • Enhancer Elements, Genetic
  • Developmental Biology
  • Chromatin
  • Animals
 

Citation

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Krangel, M. S. (2016). The Ties that Bind (the Igh Locus). Trends Genet, 32(5), 253–255. https://doi.org/10.1016/j.tig.2016.03.003
Krangel, Michael S. “The Ties that Bind (the Igh Locus).Trends Genet 32, no. 5 (May 2016): 253–55. https://doi.org/10.1016/j.tig.2016.03.003.
Krangel MS. The Ties that Bind (the Igh Locus). Trends Genet. 2016 May;32(5):253–5.
Krangel, Michael S. “The Ties that Bind (the Igh Locus).Trends Genet, vol. 32, no. 5, May 2016, pp. 253–55. Pubmed, doi:10.1016/j.tig.2016.03.003.
Krangel MS. The Ties that Bind (the Igh Locus). Trends Genet. 2016 May;32(5):253–255.
Journal cover image

Published In

Trends Genet

DOI

ISSN

0168-9525

Publication Date

May 2016

Volume

32

Issue

5

Start / End Page

253 / 255

Location

England

Related Subject Headings

  • VDJ Recombinases
  • Transcription, Genetic
  • Recombination, Genetic
  • Mice
  • Immunoglobulins
  • Humans
  • Enhancer Elements, Genetic
  • Developmental Biology
  • Chromatin
  • Animals