Depletion of myocardial high energy phosphates by induction of ventricular fibrillation prior to cardioplegic arrest.
Publication
, Journal Article
Levett, JM; Kadowaki, MH; Ip, JH; Karp, RB
Published in: J Cardiovasc Surg (Torino)
1990
The effects of a short period of ventricular fibrillation on myocardial high energy phosphates were assessed in two groups of rats. Group 1 underwent hypothermic crystalloid cardioplegia infusion and aortic cross-clamping. In Group 2, cardioplegia and cross-clamping were preceded by ten seconds of induced ventricular fibrillation. In rat hearts that had undergone ventricular fibrillation, adenosine triphosphate levels averaged only 70% (p less than .0001) and creatine phosphate levels averaged only 60% (p less than .0005) of levels measured following standard cardioplegic arrest without ventricular fibrillation. These findings are of potential importance in both routine cardiac surgical procedures and in organ procurement.
Duke Scholars
Published In
J Cardiovasc Surg (Torino)
ISSN
0021-9509
Publication Date
1990
Volume
31
Issue
2
Start / End Page
209 / 212
Location
Italy
Related Subject Headings
- Ventricular Fibrillation
- Tissue and Organ Procurement
- Time Factors
- Rats, Inbred Strains
- Rats
- Phosphocreatine
- Myocardium
- Male
- Heart Arrest, Induced
- Cardiovascular System & Hematology
Citation
APA
Chicago
ICMJE
MLA
NLM
Levett, J. M., Kadowaki, M. H., Ip, J. H., & Karp, R. B. (1990). Depletion of myocardial high energy phosphates by induction of ventricular fibrillation prior to cardioplegic arrest. J Cardiovasc Surg (Torino), 31(2), 209–212.
Levett, J. M., M. H. Kadowaki, J. H. Ip, and R. B. Karp. “Depletion of myocardial high energy phosphates by induction of ventricular fibrillation prior to cardioplegic arrest.” J Cardiovasc Surg (Torino) 31, no. 2 (1990): 209–12.
Levett JM, Kadowaki MH, Ip JH, Karp RB. Depletion of myocardial high energy phosphates by induction of ventricular fibrillation prior to cardioplegic arrest. J Cardiovasc Surg (Torino). 1990;31(2):209–12.
Levett, J. M., et al. “Depletion of myocardial high energy phosphates by induction of ventricular fibrillation prior to cardioplegic arrest.” J Cardiovasc Surg (Torino), vol. 31, no. 2, 1990, pp. 209–12.
Levett JM, Kadowaki MH, Ip JH, Karp RB. Depletion of myocardial high energy phosphates by induction of ventricular fibrillation prior to cardioplegic arrest. J Cardiovasc Surg (Torino). 1990;31(2):209–212.
Published In
J Cardiovasc Surg (Torino)
ISSN
0021-9509
Publication Date
1990
Volume
31
Issue
2
Start / End Page
209 / 212
Location
Italy
Related Subject Headings
- Ventricular Fibrillation
- Tissue and Organ Procurement
- Time Factors
- Rats, Inbred Strains
- Rats
- Phosphocreatine
- Myocardium
- Male
- Heart Arrest, Induced
- Cardiovascular System & Hematology