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Carcinoma of the lung in the absence of asbestosis: The value of lung fiber burden analysis.

Publication ,  Journal Article
Roggli, VL; Sporn, TA
Published in: Ultrastruct Pathol
2016

Asbestos is universally recognized as a carcinogen for the lower respiratory tract. However, asbestos is a contributory factor in a small fraction of lung cancers, the vast majority of which are related to cigarette smoking. The challenge for the pathologist is to determine when a lung cancer may be attributed to past asbestos exposure. The finding of asbestosis either clinically or pathologically is a useful marker for such a determination. However, in the absence of asbestosis, it has been suggested that a fiber burden as determined by analytical electron microscopy within the range of asbestosis is sufficient for determination of a causal contribution. We report here an example of a case of lung cancer in which fiber burden studies showed an asbestos concentration within the range of asbestosis as determined by scanning electron microscopy (SEM).

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Published In

Ultrastruct Pathol

DOI

EISSN

1521-0758

Publication Date

2016

Volume

40

Issue

3

Start / End Page

151 / 154

Location

England

Related Subject Headings

  • Spectrometry, X-Ray Emission
  • Pathology
  • Microscopy, Electron, Scanning
  • Male
  • Lung Neoplasms
  • Humans
  • Asbestosis
  • Aged
  • Adenocarcinoma
  • 3202 Clinical sciences
 

Citation

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Roggli, V. L., & Sporn, T. A. (2016). Carcinoma of the lung in the absence of asbestosis: The value of lung fiber burden analysis. Ultrastruct Pathol, 40(3), 151–154. https://doi.org/10.3109/01913123.2016.1154915
Roggli, Victor L., and Thomas A. Sporn. “Carcinoma of the lung in the absence of asbestosis: The value of lung fiber burden analysis.Ultrastruct Pathol 40, no. 3 (2016): 151–54. https://doi.org/10.3109/01913123.2016.1154915.
Roggli, Victor L., and Thomas A. Sporn. “Carcinoma of the lung in the absence of asbestosis: The value of lung fiber burden analysis.Ultrastruct Pathol, vol. 40, no. 3, 2016, pp. 151–54. Pubmed, doi:10.3109/01913123.2016.1154915.
Roggli VL, Sporn TA. Carcinoma of the lung in the absence of asbestosis: The value of lung fiber burden analysis. Ultrastruct Pathol. 2016;40(3):151–154.

Published In

Ultrastruct Pathol

DOI

EISSN

1521-0758

Publication Date

2016

Volume

40

Issue

3

Start / End Page

151 / 154

Location

England

Related Subject Headings

  • Spectrometry, X-Ray Emission
  • Pathology
  • Microscopy, Electron, Scanning
  • Male
  • Lung Neoplasms
  • Humans
  • Asbestosis
  • Aged
  • Adenocarcinoma
  • 3202 Clinical sciences