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Vaccine Therapy, Oncolytic Viruses, and Gliomas.

Publication ,  Journal Article
Desjardins, A; Vlahovic, G; Friedman, HS
Published in: Oncology (Williston Park)
March 2016

After years of active research and refinement, vaccine therapy and oncolytic viruses are becoming part of the arsenal in the treatment of gliomas. In contrast to standard treatment with radiation therapy and chemotherapy, vaccines are more specific to the patient and the tumor. The majority of ongoing vaccine trials are investigating peptide, heat shock protein, and dendritic cell vaccines. The immunosuppression triggered by the tumor itself and by its treatment is a major obstacle to vaccine and oncolytic virus therapy. Thus, combination therapy with different agents that affect the immune system will probably be necessary.

Duke Scholars

Published In

Oncology (Williston Park)

ISSN

0890-9091

Publication Date

March 2016

Volume

30

Issue

3

Start / End Page

211 / 218

Location

United States

Related Subject Headings

  • Oncolytic Viruses
  • Oncolytic Virotherapy
  • Immunotherapy, Active
  • Immune Tolerance
  • Humans
  • Glioma
  • Cancer Vaccines
  • Antineoplastic Agents
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Desjardins, A., Vlahovic, G., & Friedman, H. S. (2016). Vaccine Therapy, Oncolytic Viruses, and Gliomas. Oncology (Williston Park), 30(3), 211–218.
Desjardins, Annick, Gordana Vlahovic, and Henry S. Friedman. “Vaccine Therapy, Oncolytic Viruses, and Gliomas.Oncology (Williston Park) 30, no. 3 (March 2016): 211–18.
Desjardins A, Vlahovic G, Friedman HS. Vaccine Therapy, Oncolytic Viruses, and Gliomas. Oncology (Williston Park). 2016 Mar;30(3):211–8.
Desjardins, Annick, et al. “Vaccine Therapy, Oncolytic Viruses, and Gliomas.Oncology (Williston Park), vol. 30, no. 3, Mar. 2016, pp. 211–18.
Desjardins A, Vlahovic G, Friedman HS. Vaccine Therapy, Oncolytic Viruses, and Gliomas. Oncology (Williston Park). 2016 Mar;30(3):211–218.

Published In

Oncology (Williston Park)

ISSN

0890-9091

Publication Date

March 2016

Volume

30

Issue

3

Start / End Page

211 / 218

Location

United States

Related Subject Headings

  • Oncolytic Viruses
  • Oncolytic Virotherapy
  • Immunotherapy, Active
  • Immune Tolerance
  • Humans
  • Glioma
  • Cancer Vaccines
  • Antineoplastic Agents