Two new ursane-type triterpenoid saponins from Elsholtzia bodinieri.
Publication
, Journal Article
Zhong, J-D; Zhao, X-W; Chen, X-Q; Li, H-M; Chen, C-H; Xia, X-S; Li, R-T
Published in: Arch Pharm Res
June 2016
Two new ursane-type triterpenoid saponins, bodiniosides M (1) and N (2), along with three known saponins, oblonganosides I (3), pseudobuxussaponin B (4) and bodinioside A (5), were isolated from the aerial parts of Elsholtzia bodinieri. The structures of compounds 1 and 2 were characterized by spectroscopic data as well as acid hydrolysis and GC analysis as 3-O-β-D-xylopyranosyl-19α-hydroxy-23-acetoxy-urs-12(13)-en-28-oic acid 28-O-α-L-rhamnopyranosyl-(1-2)-β-D-glucopyranoside and 3-O-β-D-glucopyranosyl-2α,19α-dihydroxy-urs-12(13)-en-28,20β-lactone. Compounds 1 and 5 exhibited potent anti-HCV activities in vitro with a selective index of 6.53 and 4.41, respectively.
Duke Scholars
Published In
Arch Pharm Res
DOI
EISSN
1976-3786
Publication Date
June 2016
Volume
39
Issue
6
Start / End Page
771 / 777
Location
Korea (South)
Related Subject Headings
- Triterpenes
- Saponins
- Plant Components, Aerial
- Pharmacology & Pharmacy
- Molecular Structure
- Lamiaceae
- Hepacivirus
- Drug Discovery
- Cell Survival
- Cell Line
Citation
APA
Chicago
ICMJE
MLA
NLM
Zhong, J.-D., Zhao, X.-W., Chen, X.-Q., Li, H.-M., Chen, C.-H., Xia, X.-S., & Li, R.-T. (2016). Two new ursane-type triterpenoid saponins from Elsholtzia bodinieri. Arch Pharm Res, 39(6), 771–777. https://doi.org/10.1007/s12272-016-0750-8
Zhong, Jin-Dong, Xue-Wei Zhao, Xuan-Qin Chen, Hong-Mei Li, Chin-Ho Chen, Xue-Shan Xia, and Rong-Tao Li. “Two new ursane-type triterpenoid saponins from Elsholtzia bodinieri.” Arch Pharm Res 39, no. 6 (June 2016): 771–77. https://doi.org/10.1007/s12272-016-0750-8.
Zhong J-D, Zhao X-W, Chen X-Q, Li H-M, Chen C-H, Xia X-S, et al. Two new ursane-type triterpenoid saponins from Elsholtzia bodinieri. Arch Pharm Res. 2016 Jun;39(6):771–7.
Zhong, Jin-Dong, et al. “Two new ursane-type triterpenoid saponins from Elsholtzia bodinieri.” Arch Pharm Res, vol. 39, no. 6, June 2016, pp. 771–77. Pubmed, doi:10.1007/s12272-016-0750-8.
Zhong J-D, Zhao X-W, Chen X-Q, Li H-M, Chen C-H, Xia X-S, Li R-T. Two new ursane-type triterpenoid saponins from Elsholtzia bodinieri. Arch Pharm Res. 2016 Jun;39(6):771–777.
Published In
Arch Pharm Res
DOI
EISSN
1976-3786
Publication Date
June 2016
Volume
39
Issue
6
Start / End Page
771 / 777
Location
Korea (South)
Related Subject Headings
- Triterpenes
- Saponins
- Plant Components, Aerial
- Pharmacology & Pharmacy
- Molecular Structure
- Lamiaceae
- Hepacivirus
- Drug Discovery
- Cell Survival
- Cell Line