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Research Methods in Healthcare Epidemiology and Antimicrobial Stewardship: Randomized Controlled Trials.

Publication ,  Journal Article
Anderson, DJ; Juthani-Mehta, M; Morgan, DJ
Published in: Infect Control Hosp Epidemiol
June 2016

Randomized controlled trials (RCT) produce the strongest level of clinical evidence when comparing interventions. RCTs are technically difficult, costly, and require specific considerations including the use of patient- and cluster-level randomization and outcome selection. In this methods paper, we focus on key considerations for RCT methods in healthcare epidemiology and antimicrobial stewardship (HE&AS) research, including the need for cluster randomization, conduct at multiple sites, behavior modification interventions, and difficulty with identifying appropriate outcomes. We review key RCTs in HE&AS with a focus on advantages and disadvantages of methods used. A checklist is provided to aid in the development of RCTs in HE&AS. Infect Control Hosp Epidemiol 2016;37:629-634.

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Published In

Infect Control Hosp Epidemiol

DOI

EISSN

1559-6834

Publication Date

June 2016

Volume

37

Issue

6

Start / End Page

629 / 634

Location

United States

Related Subject Headings

  • Randomized Controlled Trials as Topic
  • Humans
  • Health Services Research
  • Epidemiology
  • Antimicrobial Stewardship
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 11 Medical and Health Sciences
 

Citation

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ICMJE
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Anderson, D. J., Juthani-Mehta, M., & Morgan, D. J. (2016). Research Methods in Healthcare Epidemiology and Antimicrobial Stewardship: Randomized Controlled Trials. Infect Control Hosp Epidemiol, 37(6), 629–634. https://doi.org/10.1017/ice.2016.93
Anderson, Deverick J., Manisha Juthani-Mehta, and Daniel J. Morgan. “Research Methods in Healthcare Epidemiology and Antimicrobial Stewardship: Randomized Controlled Trials.Infect Control Hosp Epidemiol 37, no. 6 (June 2016): 629–34. https://doi.org/10.1017/ice.2016.93.
Anderson DJ, Juthani-Mehta M, Morgan DJ. Research Methods in Healthcare Epidemiology and Antimicrobial Stewardship: Randomized Controlled Trials. Infect Control Hosp Epidemiol. 2016 Jun;37(6):629–34.
Anderson, Deverick J., et al. “Research Methods in Healthcare Epidemiology and Antimicrobial Stewardship: Randomized Controlled Trials.Infect Control Hosp Epidemiol, vol. 37, no. 6, June 2016, pp. 629–34. Pubmed, doi:10.1017/ice.2016.93.
Anderson DJ, Juthani-Mehta M, Morgan DJ. Research Methods in Healthcare Epidemiology and Antimicrobial Stewardship: Randomized Controlled Trials. Infect Control Hosp Epidemiol. 2016 Jun;37(6):629–634.
Journal cover image

Published In

Infect Control Hosp Epidemiol

DOI

EISSN

1559-6834

Publication Date

June 2016

Volume

37

Issue

6

Start / End Page

629 / 634

Location

United States

Related Subject Headings

  • Randomized Controlled Trials as Topic
  • Humans
  • Health Services Research
  • Epidemiology
  • Antimicrobial Stewardship
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 11 Medical and Health Sciences