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Comorbidities in patients with all-positive symptoms on sinonasal outcomes test quality-of-life instrument.

Publication ,  Journal Article
Caten, A; Johnson, C; Jang, D; Gurrola, J; Kountakis, S
Published in: Laryngoscope
December 2015

OBJECTIVES/HYPOTHESIS: The Sinonasal Outcomes Test-20 (SNOT-20) is a validated tool to assess treatment outcomes in patients with chronic rhinosinusitis (CRS). In the clinic, we observed that patients who responded with a positive score on all 20 items of the SNOT-20 questionnaire (pan-positive patients) often did not have evidence of CRS upon workup. Many of these patients had other underlying diseases contributing to their complaints. METHODS: Analysis of prospectively collected data was performed to identify SNOT-20 pan-positive patients and compare them to 100 consecutive non-pan-positive patients who served as the control group. The following parameters were compared between the two patient groups: presence or absence of chronic diseases such as obstructive sleep apnea, depression, anxiety, fibromyalgia, chronic pain, headaches, temporomandibular joint disease, and arthritis--in addition to sinus computed-tomography Lund-McKay scores and nasal endoscopy Lund-Kennedy scores. We also reviewed the medication list of each patient to look for the possible presence of mental illness. Statistical analysis was performed using the chi-squared and Student t test. RESULTS: One hundred twenty-two pan-positive patients were identified in our database collected from 2003 to 2011. Pan-positive patients had higher incidence of depression, fibromyalgia, anxiety, pain, headache, and use of depression medications--and they also had higher SNOT-20 and endoscopy scores when compared to controls (P < 0.05). Pan-positive patients were more likely female (P < 0.05), but age and race differences did not reach statistical significance. CONCLUSION: The SNOT-20 questionnaire assists clinicians to monitor outcomes in patients treated for CRS. However, clinicians should suspect other underlying chronic conditions in SNOT-20 pan-positive patients. LEVEL OF EVIDENCE: 3B.

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Published In

Laryngoscope

DOI

EISSN

1531-4995

Publication Date

December 2015

Volume

125

Issue

12

Start / End Page

2648 / 2652

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Sinusitis
  • Rhinitis
  • Quality of Life
  • Prospective Studies
  • Patient Outcome Assessment
  • Otorhinolaryngology
  • Nasal Surgical Procedures
  • Middle Aged
  • Male
 

Citation

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ICMJE
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Caten, A., Johnson, C., Jang, D., Gurrola, J., & Kountakis, S. (2015). Comorbidities in patients with all-positive symptoms on sinonasal outcomes test quality-of-life instrument. Laryngoscope, 125(12), 2648–2652. https://doi.org/10.1002/lary.25456
Caten, Alexander, Christopher Johnson, David Jang, Jose Gurrola, and Stilianos Kountakis. “Comorbidities in patients with all-positive symptoms on sinonasal outcomes test quality-of-life instrument.Laryngoscope 125, no. 12 (December 2015): 2648–52. https://doi.org/10.1002/lary.25456.
Caten A, Johnson C, Jang D, Gurrola J, Kountakis S. Comorbidities in patients with all-positive symptoms on sinonasal outcomes test quality-of-life instrument. Laryngoscope. 2015 Dec;125(12):2648–52.
Caten, Alexander, et al. “Comorbidities in patients with all-positive symptoms on sinonasal outcomes test quality-of-life instrument.Laryngoscope, vol. 125, no. 12, Dec. 2015, pp. 2648–52. Pubmed, doi:10.1002/lary.25456.
Caten A, Johnson C, Jang D, Gurrola J, Kountakis S. Comorbidities in patients with all-positive symptoms on sinonasal outcomes test quality-of-life instrument. Laryngoscope. 2015 Dec;125(12):2648–2652.
Journal cover image

Published In

Laryngoscope

DOI

EISSN

1531-4995

Publication Date

December 2015

Volume

125

Issue

12

Start / End Page

2648 / 2652

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Sinusitis
  • Rhinitis
  • Quality of Life
  • Prospective Studies
  • Patient Outcome Assessment
  • Otorhinolaryngology
  • Nasal Surgical Procedures
  • Middle Aged
  • Male