Skip to main content

Outcome results of the 1996-1999 patterns of care survey of the national practice for patients receiving radiation therapy for carcinoma of the esophagus.

Publication ,  Journal Article
Suntharalingam, M; Moughan, J; Coia, LR; Krasna, MJ; Kachnic, L; Haller, DG; Willet, CG; John, MJ; Minsky, BD; Owen, JB
Published in: J Clin Oncol
April 1, 2005

PURPOSE: A Patterns of Care Study of patients treated from 1996 to 1999 evaluated the national practice for patients receiving radiation therapy for carcinoma of the esophagus in the United States. METHODS: A national survey was conducted at 59 institutions in a stratified random sample selected from a master list of radiation therapy facilities throughout the United States. Patient, tumor, and treatment characteristics were evaluated. Multivariate comparisons of survival times were made using the Cox proportional hazards model. RESULTS: Adenocarcinoma was diagnosed in 51% of patients and squamous cell carcinoma in 49% of patients. Sixteen percent of patients were clinical stage (CS) I (using the 1983 American Joint Committee on Cancer system), 39% were CS II, and 33% were CS III. Significant variables in the multivariate analysis of survival times included clinical stage, treatment approach, and facility size. Patients with CS III disease had a higher hazard risk of death as compared with CS I patients (hazard ratio [HR], 2.01; P = .001), whereas those treated with chemoradiotherapy followed by surgery (HR, 0.32; P < .0001) had a decreased risk of death compared with chemoradiotherapy-only patients. Patients at small centers had a higher risk of death (HR, 1.32; P = .03) compared with patients treated at larger facilities. CONCLUSION: Concurrent chemoradiotherapy continued to be the most commonly utilized treatment approach during the time period studied. The observation that patients undergoing surgical resection following chemoradiation have a decreased HR or chance of death compared with other treatment schemes supports the need for a randomized trial comparing these strategies.

Duke Scholars

Published In

J Clin Oncol

DOI

ISSN

0732-183X

Publication Date

April 1, 2005

Volume

23

Issue

10

Start / End Page

2325 / 2331

Location

United States

Related Subject Headings

  • United States
  • Survival Analysis
  • Risk Factors
  • Practice Patterns, Physicians'
  • Oncology & Carcinogenesis
  • Multivariate Analysis
  • Middle Aged
  • Male
  • Humans
  • Health Care Surveys
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Suntharalingam, M., Moughan, J., Coia, L. R., Krasna, M. J., Kachnic, L., Haller, D. G., … Owen, J. B. (2005). Outcome results of the 1996-1999 patterns of care survey of the national practice for patients receiving radiation therapy for carcinoma of the esophagus. J Clin Oncol, 23(10), 2325–2331. https://doi.org/10.1200/JCO.2005.00.448
Suntharalingam, Mohan, Jennifer Moughan, Lawrence R. Coia, Mark J. Krasna, Lisa Kachnic, Daniel G. Haller, Christopher G. Willet, Madhu J. John, Bruce D. Minsky, and Jean B. Owen. “Outcome results of the 1996-1999 patterns of care survey of the national practice for patients receiving radiation therapy for carcinoma of the esophagus.J Clin Oncol 23, no. 10 (April 1, 2005): 2325–31. https://doi.org/10.1200/JCO.2005.00.448.
Suntharalingam M, Moughan J, Coia LR, Krasna MJ, Kachnic L, Haller DG, et al. Outcome results of the 1996-1999 patterns of care survey of the national practice for patients receiving radiation therapy for carcinoma of the esophagus. J Clin Oncol. 2005 Apr 1;23(10):2325–31.
Suntharalingam, Mohan, et al. “Outcome results of the 1996-1999 patterns of care survey of the national practice for patients receiving radiation therapy for carcinoma of the esophagus.J Clin Oncol, vol. 23, no. 10, Apr. 2005, pp. 2325–31. Pubmed, doi:10.1200/JCO.2005.00.448.
Suntharalingam M, Moughan J, Coia LR, Krasna MJ, Kachnic L, Haller DG, Willet CG, John MJ, Minsky BD, Owen JB. Outcome results of the 1996-1999 patterns of care survey of the national practice for patients receiving radiation therapy for carcinoma of the esophagus. J Clin Oncol. 2005 Apr 1;23(10):2325–2331.

Published In

J Clin Oncol

DOI

ISSN

0732-183X

Publication Date

April 1, 2005

Volume

23

Issue

10

Start / End Page

2325 / 2331

Location

United States

Related Subject Headings

  • United States
  • Survival Analysis
  • Risk Factors
  • Practice Patterns, Physicians'
  • Oncology & Carcinogenesis
  • Multivariate Analysis
  • Middle Aged
  • Male
  • Humans
  • Health Care Surveys