Role of C1q complement fixing antibody assay in therapeutic plasma exchange management of pediatric cardiac antibody mediated rejection.
Publication
, Journal Article
Onwuemene, OA; Heath, DM; Hartman, C; Wong, ECC
Published in: J Clin Apher
August 2017
Pediatric cardiac transplant patients with antibody-mediated rejection (AMR) often undergo therapeutic plasma exchange (TPE) to remove pathologic donor specific antibodies (DSA). In cases where DSA persist, it is unclear how long TPE should be continued. We report a case of a 17-year-old cardiac transplant patient with AMR where use of a C1q complement fixing antibody assay helped guide TPE cessation. This report adds to the existing literature that highlights the potential clinical significance of C1q antibodies in AMR management.
Duke Scholars
Published In
J Clin Apher
DOI
EISSN
1098-1101
Publication Date
August 2017
Volume
32
Issue
4
Start / End Page
279 / 281
Location
United States
Related Subject Headings
- Plasma Exchange
- Male
- Isoantibodies
- Immunologic Tests
- Humans
- Heart Transplantation
- Graft Rejection
- Complement C1q
- Cardiovascular System & Hematology
- Adolescent
Citation
APA
Chicago
ICMJE
MLA
NLM
Onwuemene, O. A., Heath, D. M., Hartman, C., & Wong, E. C. C. (2017). Role of C1q complement fixing antibody assay in therapeutic plasma exchange management of pediatric cardiac antibody mediated rejection. J Clin Apher, 32(4), 279–281. https://doi.org/10.1002/jca.21488
Onwuemene, Oluwatoyosi A., Deneen M. Heath, Carol Hartman, and Edward C. C. Wong. “Role of C1q complement fixing antibody assay in therapeutic plasma exchange management of pediatric cardiac antibody mediated rejection.” J Clin Apher 32, no. 4 (August 2017): 279–81. https://doi.org/10.1002/jca.21488.
Onwuemene OA, Heath DM, Hartman C, Wong ECC. Role of C1q complement fixing antibody assay in therapeutic plasma exchange management of pediatric cardiac antibody mediated rejection. J Clin Apher. 2017 Aug;32(4):279–81.
Onwuemene, Oluwatoyosi A., et al. “Role of C1q complement fixing antibody assay in therapeutic plasma exchange management of pediatric cardiac antibody mediated rejection.” J Clin Apher, vol. 32, no. 4, Aug. 2017, pp. 279–81. Pubmed, doi:10.1002/jca.21488.
Onwuemene OA, Heath DM, Hartman C, Wong ECC. Role of C1q complement fixing antibody assay in therapeutic plasma exchange management of pediatric cardiac antibody mediated rejection. J Clin Apher. 2017 Aug;32(4):279–281.
Published In
J Clin Apher
DOI
EISSN
1098-1101
Publication Date
August 2017
Volume
32
Issue
4
Start / End Page
279 / 281
Location
United States
Related Subject Headings
- Plasma Exchange
- Male
- Isoantibodies
- Immunologic Tests
- Humans
- Heart Transplantation
- Graft Rejection
- Complement C1q
- Cardiovascular System & Hematology
- Adolescent