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Sarcopenia in Patients with Chronic Liver Disease: Can It Be Altered by Diet and Exercise?

Publication ,  Journal Article
Kappus, MR; Mendoza, MS; Nguyen, D; Medici, V; McClave, SA
Published in: Curr Gastroenterol Rep
August 2016

Sarcopenia, a loss of muscle mass, is being increasingly recognized to have a deleterious effect on outcomes in patients with chronic liver disease. Factors related to diet and the inflammatory nature of chronic liver disease contribute to the occurrence of sarcopenia in these patients. Sarcopenia adversely influences quality of life, performance, morbidity, success of transplantation, and even mortality. Specific deficiencies in macronutrients (protein, polyunsaturated fatty acids) and micronutrients (vitamins C, D, and E, carotenoids, and selenium) have been linked to sarcopenia. Lessons learned from nutritional therapy in geriatric patient populations may provide strategies to manage sarcopenia in patients with liver disease. Combining diet modification and nutrient supplementation with an organized program of exercise may help ameliorate or even reverse the effects of sarcopenia on an already complex disease process.

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Published In

Curr Gastroenterol Rep

DOI

EISSN

1534-312X

Publication Date

August 2016

Volume

18

Issue

8

Start / End Page

43

Location

United States

Related Subject Headings

  • Vitamin D
  • Sarcopenia
  • Liver Diseases
  • Humans
  • Gastroenterology & Hepatology
  • Fatty Acids, Unsaturated
  • Exercise
  • Dietary Supplements
  • Combined Modality Therapy
  • Chronic Disease
 

Citation

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Kappus, M. R., Mendoza, M. S., Nguyen, D., Medici, V., & McClave, S. A. (2016). Sarcopenia in Patients with Chronic Liver Disease: Can It Be Altered by Diet and Exercise? Curr Gastroenterol Rep, 18(8), 43. https://doi.org/10.1007/s11894-016-0516-y
Kappus, Matthew R., Mardeli Saire Mendoza, Douglas Nguyen, Valentina Medici, and Stephen A. McClave. “Sarcopenia in Patients with Chronic Liver Disease: Can It Be Altered by Diet and Exercise?Curr Gastroenterol Rep 18, no. 8 (August 2016): 43. https://doi.org/10.1007/s11894-016-0516-y.
Kappus MR, Mendoza MS, Nguyen D, Medici V, McClave SA. Sarcopenia in Patients with Chronic Liver Disease: Can It Be Altered by Diet and Exercise? Curr Gastroenterol Rep. 2016 Aug;18(8):43.
Kappus, Matthew R., et al. “Sarcopenia in Patients with Chronic Liver Disease: Can It Be Altered by Diet and Exercise?Curr Gastroenterol Rep, vol. 18, no. 8, Aug. 2016, p. 43. Pubmed, doi:10.1007/s11894-016-0516-y.
Kappus MR, Mendoza MS, Nguyen D, Medici V, McClave SA. Sarcopenia in Patients with Chronic Liver Disease: Can It Be Altered by Diet and Exercise? Curr Gastroenterol Rep. 2016 Aug;18(8):43.
Journal cover image

Published In

Curr Gastroenterol Rep

DOI

EISSN

1534-312X

Publication Date

August 2016

Volume

18

Issue

8

Start / End Page

43

Location

United States

Related Subject Headings

  • Vitamin D
  • Sarcopenia
  • Liver Diseases
  • Humans
  • Gastroenterology & Hepatology
  • Fatty Acids, Unsaturated
  • Exercise
  • Dietary Supplements
  • Combined Modality Therapy
  • Chronic Disease