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An assessment of ST-segment measurement variability between two core electrocardiogram laboratories.

Publication ,  Journal Article
Dianati Maleki, N; Stocke, K; Zheng, Y; Westerhout, CM; Fu, Y; Chaitman, BR; Awad, A; Jagasia, P; Armstrong, PW
Published in: J Electrocardiol
2014

OBJECTIVES: We evaluated inter-reader agreement of the ST-segment between two electrocardiogram (ECG) core laboratories. BACKGROUND: Accurate measurement of the ST-segment is key to diagnosis and management of acute coronary syndromes (ACS). Clinical trials also rely on adherence to the pre-specified ECG eligibility criteria. METHODS: 150 patients (100 ST-segment elevation (STE)-ACS, 50 non-STE-ACS) were selected. An experienced ECG reader from each laboratory measured ST-segment deviation on the baseline ECGs (nearest 0.1mm). RESULTS: ∑ST-segment deviation showed excellent inter-reader agreement (R=0.965, intraclass correlation coefficient (ICC) 0.949, 95% CI (0.930-0.963)). Similar agreement was observed when ∑ST-segment elevation (∑STE) and ∑ST-segment depression (∑STD) were assessed separately. Better agreement was evident in STE-ACS cohort (ICC (95% CI): 0.968 (0.953-0.978, 0.969 (0.954-0.979), 0.931 (0.899-0.953)) compared to NSTE-ACS patients (ICC (95% CI): 0.860 (0.768-0.917), 0.816 (0.699-0.890), 0.753 (0.605-0.851) across measurement of ∑ST-segment deviation, ∑STE, and ∑STD. CONCLUSIONS: We demonstrated excellent agreement on ST-segment measurements between two experienced readers from two ECG core laboratories.

Duke Scholars

Published In

J Electrocardiol

DOI

EISSN

1532-8430

Publication Date

2014

Volume

47

Issue

1

Start / End Page

38 / 44

Location

United States

Related Subject Headings

  • Sensitivity and Specificity
  • Reproducibility of Results
  • Observer Variation
  • Myocardial Infarction
  • Missouri
  • Middle Aged
  • Male
  • Laboratories, Hospital
  • Humans
  • Female
 

Citation

APA
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ICMJE
MLA
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Dianati Maleki, N., Stocke, K., Zheng, Y., Westerhout, C. M., Fu, Y., Chaitman, B. R., … Armstrong, P. W. (2014). An assessment of ST-segment measurement variability between two core electrocardiogram laboratories. J Electrocardiol, 47(1), 38–44. https://doi.org/10.1016/j.jelectrocard.2013.10.005
Dianati Maleki, Neda, Karen Stocke, Yinggan Zheng, Cynthia M. Westerhout, Yuling Fu, Bernard R. Chaitman, Ahmed Awad, Pushpa Jagasia, and Paul W. Armstrong. “An assessment of ST-segment measurement variability between two core electrocardiogram laboratories.J Electrocardiol 47, no. 1 (2014): 38–44. https://doi.org/10.1016/j.jelectrocard.2013.10.005.
Dianati Maleki N, Stocke K, Zheng Y, Westerhout CM, Fu Y, Chaitman BR, et al. An assessment of ST-segment measurement variability between two core electrocardiogram laboratories. J Electrocardiol. 2014;47(1):38–44.
Dianati Maleki, Neda, et al. “An assessment of ST-segment measurement variability between two core electrocardiogram laboratories.J Electrocardiol, vol. 47, no. 1, 2014, pp. 38–44. Pubmed, doi:10.1016/j.jelectrocard.2013.10.005.
Dianati Maleki N, Stocke K, Zheng Y, Westerhout CM, Fu Y, Chaitman BR, Awad A, Jagasia P, Armstrong PW. An assessment of ST-segment measurement variability between two core electrocardiogram laboratories. J Electrocardiol. 2014;47(1):38–44.
Journal cover image

Published In

J Electrocardiol

DOI

EISSN

1532-8430

Publication Date

2014

Volume

47

Issue

1

Start / End Page

38 / 44

Location

United States

Related Subject Headings

  • Sensitivity and Specificity
  • Reproducibility of Results
  • Observer Variation
  • Myocardial Infarction
  • Missouri
  • Middle Aged
  • Male
  • Laboratories, Hospital
  • Humans
  • Female