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Suprathreshold heat pain response predicts activity-related pain, but not rest-related pain, in an exercise-induced injury model.

Publication ,  Journal Article
Coronado, RA; Simon, CB; Valencia, C; Parr, JJ; Borsa, PA; George, SZ
Published in: PLoS One
2014

Exercise-induced injury models are advantageous for studying pain since the onset of pain is controlled and both pre-injury and post-injury factors can be utilized as explanatory variables or predictors. In these studies, rest-related pain is often considered the primary dependent variable or outcome, as opposed to a measure of activity-related pain. Additionally, few studies include pain sensitivity measures as predictors. In this study, we examined the influence of pre-injury and post-injury factors, including pain sensitivity, for induced rest and activity-related pain following exercise induced muscle injury. The overall goal of this investigation was to determine if there were convergent or divergent predictors of rest and activity-related pain. One hundred forty-three participants provided demographic, psychological, and pain sensitivity information and underwent a standard fatigue trial of resistance exercise to induce injury of the dominant shoulder. Pain at rest and during active and resisted shoulder motion were measured at 48- and 96-hours post-injury. Separate hierarchical models were generated for assessing the influence of pre-injury and post-injury factors on 48- and 96-hour rest-related and activity-related pain. Overall, we did not find a universal predictor of pain across all models. However, pre-injury and post-injury suprathreshold heat pain response (SHPR), a pain sensitivity measure, was a consistent predictor of activity-related pain, even after controlling for known psychological factors. These results suggest there is differential prediction of pain. A measure of pain sensitivity such as SHPR appears more influential for activity-related pain, but not rest-related pain, and may reflect different underlying processes involved during pain appraisal.

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Published In

PLoS One

DOI

EISSN

1932-6203

Publication Date

2014

Volume

9

Issue

9

Start / End Page

e108699

Location

United States

Related Subject Headings

  • Young Adult
  • Shoulder Pain
  • Rest
  • Regression Analysis
  • Pain Threshold
  • Models, Biological
  • Middle Aged
  • Male
  • Isometric Contraction
  • Humans
 

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ICMJE
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Coronado, R. A., Simon, C. B., Valencia, C., Parr, J. J., Borsa, P. A., & George, S. Z. (2014). Suprathreshold heat pain response predicts activity-related pain, but not rest-related pain, in an exercise-induced injury model. PLoS One, 9(9), e108699. https://doi.org/10.1371/journal.pone.0108699
Coronado, Rogelio A., Corey B. Simon, Carolina Valencia, Jeffrey J. Parr, Paul A. Borsa, and Steven Z. George. “Suprathreshold heat pain response predicts activity-related pain, but not rest-related pain, in an exercise-induced injury model.PLoS One 9, no. 9 (2014): e108699. https://doi.org/10.1371/journal.pone.0108699.
Coronado RA, Simon CB, Valencia C, Parr JJ, Borsa PA, George SZ. Suprathreshold heat pain response predicts activity-related pain, but not rest-related pain, in an exercise-induced injury model. PLoS One. 2014;9(9):e108699.
Coronado, Rogelio A., et al. “Suprathreshold heat pain response predicts activity-related pain, but not rest-related pain, in an exercise-induced injury model.PLoS One, vol. 9, no. 9, 2014, p. e108699. Pubmed, doi:10.1371/journal.pone.0108699.
Coronado RA, Simon CB, Valencia C, Parr JJ, Borsa PA, George SZ. Suprathreshold heat pain response predicts activity-related pain, but not rest-related pain, in an exercise-induced injury model. PLoS One. 2014;9(9):e108699.

Published In

PLoS One

DOI

EISSN

1932-6203

Publication Date

2014

Volume

9

Issue

9

Start / End Page

e108699

Location

United States

Related Subject Headings

  • Young Adult
  • Shoulder Pain
  • Rest
  • Regression Analysis
  • Pain Threshold
  • Models, Biological
  • Middle Aged
  • Male
  • Isometric Contraction
  • Humans