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Acute coronary syndromes in women and men.

Publication ,  Journal Article
Pagidipati, NJ; Peterson, ED
Published in: Nat Rev Cardiol
August 2016

Evidence of sex-related disparities in the care and outcomes of patients with acute coronary syndrome (ACS) emerged >30 years ago, and yet the mechanisms behind these sex-specific differences remain unclear. In this Review, we discuss the current literature on differences between women and men in the clinical presentation, pathophysiology, evaluation, management, and outcomes of ACS. Although the symptoms of ACS and the benefits of therapy generally overlap between women and men, women continue to receive less-aggressive invasive and pharmacological therapy than men. In addition, young women in particular have worse short-term and long-term outcomes than men. To understand better the mechanisms behind these continued disparities, we have identified areas of future research that need to be urgently addressed in fields that range from clinical evaluation and management, to increasing representation of women in research.

Duke Scholars

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Published In

Nat Rev Cardiol

DOI

EISSN

1759-5010

Publication Date

August 2016

Volume

13

Issue

8

Start / End Page

471 / 480

Location

England

Related Subject Headings

  • Treatment Outcome
  • Time Factors
  • Sex Factors
  • Risk Factors
  • Middle Aged
  • Male
  • Life Style
  • Humans
  • Healthcare Disparities
  • Health Status Disparities
 

Citation

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Pagidipati, N. J., & Peterson, E. D. (2016). Acute coronary syndromes in women and men. Nat Rev Cardiol, 13(8), 471–480. https://doi.org/10.1038/nrcardio.2016.89
Pagidipati, Neha J., and Eric D. Peterson. “Acute coronary syndromes in women and men.Nat Rev Cardiol 13, no. 8 (August 2016): 471–80. https://doi.org/10.1038/nrcardio.2016.89.
Pagidipati NJ, Peterson ED. Acute coronary syndromes in women and men. Nat Rev Cardiol. 2016 Aug;13(8):471–80.
Pagidipati, Neha J., and Eric D. Peterson. “Acute coronary syndromes in women and men.Nat Rev Cardiol, vol. 13, no. 8, Aug. 2016, pp. 471–80. Pubmed, doi:10.1038/nrcardio.2016.89.
Pagidipati NJ, Peterson ED. Acute coronary syndromes in women and men. Nat Rev Cardiol. 2016 Aug;13(8):471–480.

Published In

Nat Rev Cardiol

DOI

EISSN

1759-5010

Publication Date

August 2016

Volume

13

Issue

8

Start / End Page

471 / 480

Location

England

Related Subject Headings

  • Treatment Outcome
  • Time Factors
  • Sex Factors
  • Risk Factors
  • Middle Aged
  • Male
  • Life Style
  • Humans
  • Healthcare Disparities
  • Health Status Disparities