The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease.
Publication
, Journal Article
Cooke, KR; Luznik, L; Sarantopoulos, S; Hakim, FT; Jagasia, M; Fowler, DH; van den Brink, MRM; Hansen, JA; Parkman, R; Miklos, DB; Martin, PJ ...
Published in: Biol Blood Marrow Transplant
February 2017
Chronic graft-versus-host disease (GVHD) is the leading cause of late, nonrelapse mortality and disability in allogeneic hematopoietic cell transplantation recipients and a major obstacle to improving outcomes. The biology of chronic GVHD remains enigmatic, but understanding the underpinnings of the immunologic mechanisms responsible for the initiation and progression of disease is fundamental to developing effective prevention and treatment strategies. The goals of this task force review are as follows: This document is intended as a review of our understanding of chronic GVHD biology and therapies resulting from preclinical studies, and as a platform for developing innovative clinical strategies to prevent and treat chronic GVHD.
Duke Scholars
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Published In
Biol Blood Marrow Transplant
DOI
EISSN
1523-6536
Publication Date
February 2017
Volume
23
Issue
2
Start / End Page
211 / 234
Location
United States
Related Subject Headings
- Wound Healing
- Transplantation Immunology
- Terminology as Topic
- T-Lymphocyte Subsets
- Organ Specificity
- Models, Immunological
- Models, Animal
- Mice
- Interferon-gamma
- Inflammation
Citation
APA
Chicago
ICMJE
MLA
NLM
Cooke, K. R., Luznik, L., Sarantopoulos, S., Hakim, F. T., Jagasia, M., Fowler, D. H., … Blazar, B. R. (2017). The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease. Biol Blood Marrow Transplant, 23(2), 211–234. https://doi.org/10.1016/j.bbmt.2016.09.023
Cooke, Kenneth R., Leo Luznik, Stefanie Sarantopoulos, Frances T. Hakim, Madan Jagasia, Daniel H. Fowler, Marcel R. M. van den Brink, et al. “The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease.” Biol Blood Marrow Transplant 23, no. 2 (February 2017): 211–34. https://doi.org/10.1016/j.bbmt.2016.09.023.
Cooke KR, Luznik L, Sarantopoulos S, Hakim FT, Jagasia M, Fowler DH, et al. The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease. Biol Blood Marrow Transplant. 2017 Feb;23(2):211–34.
Cooke, Kenneth R., et al. “The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease.” Biol Blood Marrow Transplant, vol. 23, no. 2, Feb. 2017, pp. 211–34. Pubmed, doi:10.1016/j.bbmt.2016.09.023.
Cooke KR, Luznik L, Sarantopoulos S, Hakim FT, Jagasia M, Fowler DH, van den Brink MRM, Hansen JA, Parkman R, Miklos DB, Martin PJ, Paczesny S, Vogelsang G, Pavletic S, Ritz J, Schultz KR, Blazar BR. The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease. Biol Blood Marrow Transplant. 2017 Feb;23(2):211–234.
Published In
Biol Blood Marrow Transplant
DOI
EISSN
1523-6536
Publication Date
February 2017
Volume
23
Issue
2
Start / End Page
211 / 234
Location
United States
Related Subject Headings
- Wound Healing
- Transplantation Immunology
- Terminology as Topic
- T-Lymphocyte Subsets
- Organ Specificity
- Models, Immunological
- Models, Animal
- Mice
- Interferon-gamma
- Inflammation