Huntington's-chorea fibroblasts. Cellular protein glycosylation.
Publication
, Journal Article
Hung, WY; Mold, DE; Tourian, A
Published in: Biochem J
September 15, 1980
Five cell cultures of Huntington's-chorea fibroblasts exhibit greater than normal protein and lipid glycosylation when labelled with [U-14C]glucosamine. Oligosaccharide--polypeptide chains from all molecular-weight ranges are labelled differentially on sodium dodecyl sulphate/polyacrylamide-gel electrophoresis. This difference in protein glycosylation is not accompanied by any apparent difference in general cellular protein synthesis or by a differential rate of glucosamine uptake or decreased degradation of [14C]glycosylated macromolecules. Additionally [U-14C]glucosamine exclusively labels hexosamines and sialic acid of cellular macromolecules.
Duke Scholars
Published In
Biochem J
DOI
ISSN
0264-6021
Publication Date
September 15, 1980
Volume
190
Issue
3
Start / End Page
711 / 719
Location
England
Related Subject Headings
- Proteins
- Middle Aged
- Macromolecular Substances
- Leucine
- Huntington Disease
- Humans
- Glucosamine
- Fibroblasts
- Female
- Electrophoresis, Polyacrylamide Gel
Citation
APA
Chicago
ICMJE
MLA
NLM
Hung, W. Y., Mold, D. E., & Tourian, A. (1980). Huntington's-chorea fibroblasts. Cellular protein glycosylation. Biochem J, 190(3), 711–719. https://doi.org/10.1042/bj1900711
Hung, W. Y., D. E. Mold, and A. Tourian. “Huntington's-chorea fibroblasts. Cellular protein glycosylation.” Biochem J 190, no. 3 (September 15, 1980): 711–19. https://doi.org/10.1042/bj1900711.
Hung WY, Mold DE, Tourian A. Huntington's-chorea fibroblasts. Cellular protein glycosylation. Biochem J. 1980 Sep 15;190(3):711–9.
Hung, W. Y., et al. “Huntington's-chorea fibroblasts. Cellular protein glycosylation.” Biochem J, vol. 190, no. 3, Sept. 1980, pp. 711–19. Pubmed, doi:10.1042/bj1900711.
Hung WY, Mold DE, Tourian A. Huntington's-chorea fibroblasts. Cellular protein glycosylation. Biochem J. 1980 Sep 15;190(3):711–719.
Published In
Biochem J
DOI
ISSN
0264-6021
Publication Date
September 15, 1980
Volume
190
Issue
3
Start / End Page
711 / 719
Location
England
Related Subject Headings
- Proteins
- Middle Aged
- Macromolecular Substances
- Leucine
- Huntington Disease
- Humans
- Glucosamine
- Fibroblasts
- Female
- Electrophoresis, Polyacrylamide Gel