Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony.
Publication
, Journal Article
Herman, MA; Kahn, BB
Published in: J Clin Invest
July 2006
Recent data underscore the importance of intertissue communication in the maintenance of normal glucose homeostasis. Important signals are conveyed by hormones, cytokines, and fuel substrates and are sensed through a variety of cellular mechanisms. The ability of tissues to sense and adapt to changes in metabolic status and fuel availability is altered in insulin-resistant states including type 2 diabetes. Here we review the roles of glucose and its metabolites as signaling molecules and the diverse physiologic mechanisms for glucose sensing.
Duke Scholars
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Published In
J Clin Invest
DOI
ISSN
0021-9738
Publication Date
July 2006
Volume
116
Issue
7
Start / End Page
1767 / 1775
Location
United States
Related Subject Headings
- Signal Transduction
- Immunology
- Humans
- Homeostasis
- Glucose
- Energy Metabolism
- Diabetes Mellitus, Type 2
- Carbon
- Biological Transport
- Animals
Citation
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Chicago
ICMJE
MLA
NLM
Herman, M. A., & Kahn, B. B. (2006). Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony. J Clin Invest, 116(7), 1767–1775. https://doi.org/10.1172/JCI29027
Herman, Mark A., and Barbara B. Kahn. “Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony.” J Clin Invest 116, no. 7 (July 2006): 1767–75. https://doi.org/10.1172/JCI29027.
Herman MA, Kahn BB. Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony. J Clin Invest. 2006 Jul;116(7):1767–75.
Herman, Mark A., and Barbara B. Kahn. “Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony.” J Clin Invest, vol. 116, no. 7, July 2006, pp. 1767–75. Pubmed, doi:10.1172/JCI29027.
Herman MA, Kahn BB. Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony. J Clin Invest. 2006 Jul;116(7):1767–1775.
Published In
J Clin Invest
DOI
ISSN
0021-9738
Publication Date
July 2006
Volume
116
Issue
7
Start / End Page
1767 / 1775
Location
United States
Related Subject Headings
- Signal Transduction
- Immunology
- Humans
- Homeostasis
- Glucose
- Energy Metabolism
- Diabetes Mellitus, Type 2
- Carbon
- Biological Transport
- Animals