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Novel anterior-chamber angle measurements by high-definition optical coherence tomography using the Schwalbe line as the landmark.

Publication ,  Journal Article
Cheung, CY; Zheng, C; Ho, C-L; Tun, TA; Kumar, RS; Sayyad, FE; Wong, TY; Aung, T
Published in: Br J Ophthalmol
July 2011

OBJECTIVE: To propose the Schwalbe line (SL) as a new anatomical landmark, independent of the scleral spur (SS) location, for assessing anterior chamber angle (ACA) width quantitatively with high-definition optical coherence tomography (HD-OCT). METHODS: Study subjects underwent dark-room gonioscopy and HD-OCT in one randomly selected eye. The authors developed a computer-aided program to define two new quantitative parameters for assessing ACA width: Schwalbe line-angle opening distance (SL-AOD) measured at the SL, and Schwalbe line-trabecular-iris space area (SL-TISA) measured 500 μm from the SL. The associations between SL parameters, SS parameters and gonioscopic grading were evaluated. RESULTS: Seventy-three (47 females, 26 males) subjects were recruited, the majority of whom were Chinese (89%). The authors excluded 29 images (19.9%) owing to poor image quality, leaving 117 HD-OCT images (65 nasal, 52 temporal) for analysis. SL and SS could be identified in 95% and 85% of quadrants respectively (p = 0.035). SL-AOD and SL-TISA were significantly correlated with SS parameters (all r ≥ 0.85) and gonioscopic grading (all r ≥ 0.69). In eyes with closed angles (n = 36), SL parameters showed strong correlations with gonioscopic grading (r ranged from 0.43 to 0.44). Conclusions Novel angle parameters, based on SL as a landmark, may be useful to quantify ACA width and to assess for risk of angle closure.

Duke Scholars

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Published In

Br J Ophthalmol

DOI

EISSN

1468-2079

Publication Date

July 2011

Volume

95

Issue

7

Start / End Page

955 / 959

Location

England

Related Subject Headings

  • Tomography, Optical Coherence
  • Software
  • Prospective Studies
  • Ophthalmology & Optometry
  • Male
  • Humans
  • Gonioscopy
  • Glaucoma, Angle-Closure
  • Female
  • Asian People
 

Citation

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Cheung, C. Y., Zheng, C., Ho, C.-L., Tun, T. A., Kumar, R. S., Sayyad, F. E., … Aung, T. (2011). Novel anterior-chamber angle measurements by high-definition optical coherence tomography using the Schwalbe line as the landmark. Br J Ophthalmol, 95(7), 955–959. https://doi.org/10.1136/bjo.2010.189217
Cheung, Carol Y., Ce Zheng, Ching-Lin Ho, Tin A. Tun, Rajesh S. Kumar, Fouad El Sayyad, Tien Y. Wong, and Tin Aung. “Novel anterior-chamber angle measurements by high-definition optical coherence tomography using the Schwalbe line as the landmark.Br J Ophthalmol 95, no. 7 (July 2011): 955–59. https://doi.org/10.1136/bjo.2010.189217.
Cheung CY, Zheng C, Ho C-L, Tun TA, Kumar RS, Sayyad FE, et al. Novel anterior-chamber angle measurements by high-definition optical coherence tomography using the Schwalbe line as the landmark. Br J Ophthalmol. 2011 Jul;95(7):955–9.
Cheung, Carol Y., et al. “Novel anterior-chamber angle measurements by high-definition optical coherence tomography using the Schwalbe line as the landmark.Br J Ophthalmol, vol. 95, no. 7, July 2011, pp. 955–59. Pubmed, doi:10.1136/bjo.2010.189217.
Cheung CY, Zheng C, Ho C-L, Tun TA, Kumar RS, Sayyad FE, Wong TY, Aung T. Novel anterior-chamber angle measurements by high-definition optical coherence tomography using the Schwalbe line as the landmark. Br J Ophthalmol. 2011 Jul;95(7):955–959.

Published In

Br J Ophthalmol

DOI

EISSN

1468-2079

Publication Date

July 2011

Volume

95

Issue

7

Start / End Page

955 / 959

Location

England

Related Subject Headings

  • Tomography, Optical Coherence
  • Software
  • Prospective Studies
  • Ophthalmology & Optometry
  • Male
  • Humans
  • Gonioscopy
  • Glaucoma, Angle-Closure
  • Female
  • Asian People